LLM Mart Basic
@llm-mart · Joined Jun 2026
Discover and characterize regulatory elements (enhancers, promoters, silencers, insulators, super-enhancers) using ENCODE data and the cCRE catalog. Use when the user wants to find candidate regulatory elements, identify active enhancers in a tissue, map promoter states, classify
Generate publication-ready methods sections, figure legends, supplementary tables, and data availability statements from ENCODE analysis provenance. Implements the scientific documentation standards requiring complete metadata reporting. Use when the user needs to write methods,
Conduct rigorous cross-study meta-analysis of scRNA-seq data from ENCODE, integrating multiple single-cell transcriptomic datasets for a tissue/cell type. Use when the user wants to answer "what cell types exist in my tissue and what genes define them?" by combining scRNA-seq dat
Search and explore ENCODE Project genomics data. Use when the user wants to find experiments, files, or explore what data is available for specific assays, organs, cell lines, or targets.
Set up the ENCODE Toolkit server connection. Use when the user needs help installing, configuring, or troubleshooting the ENCODE connector.
Find and work with ENCODE single-cell genomics data including scRNA-seq and scATAC-seq. Use when the user asks about single-cell experiments, cell type resolution, clustering from ENCODE data, deconvolution of bulk signals using single-cell references, or comparing single-cell vs
Track ENCODE experiments locally with publications, citations, and provenance. Use when the user wants to build a collection of experiments, manage citations, compare experiments, or track data provenance.
Query the UCSC Genome Browser REST API to retrieve regulatory tracks, DNA sequences, cCRE annotations, TF binding clusters, and track schemas for any genomic region. Use when the user wants to look up what regulatory elements exist at a genomic locus, retrieve DNA sequence under
Annotate genetic variants (GWAS hits, eQTLs, rare variants) with ENCODE functional data to interpret non-coding variation. Use when the user has variants of interest and wants to understand their regulatory context, identify causal variants from GWAS loci, assess variant impact o
Comprehensive guide for visualizing ENCODE data including deeptools heatmaps, IGV screenshots, UCSC track hubs, and publication-quality plots. Use when users need to create visualizations of ChIP-seq signal, peak landscapes, genome browser views, or any visual representation of E
Build comprehensive chromatin accessibility maps by aggregating ATAC-seq and DNase-seq narrowPeak data across multiple ENCODE experiments, donors, and labs. Use when the user wants to answer "where is chromatin accessible in my tissue?" by combining peak calls into a union peak s
Guide for multi-experiment batch operations: QC screening, batch download, comparison, and report generation across many ENCODE experiments simultaneously. Use when users need to process 5+ experiments together, create experiment comparison tables, perform batch quality checks, o
Install bioinformatics tools for ENCODE data analysis. Covers CLI tools (BWA, STAR, samtools, MACS2), R/Bioconductor packages (DESeq2, Seurat, ChIPseeker), Python packages (Scanpy, deeptools), and Nextflow pipeline infrastructure. Generates conda environments, R install scripts,
Guide for integrating CellxGene Census single-cell data with ENCODE bulk experiments. Use when users need cell-type-specific expression context for ENCODE regulatory data, want to deconvolve bulk ENCODE signals, or validate regulatory elements at single-cell resolution. Trigger o
Generate proper ENCODE citations for publications, grants, and presentations. Use when the user needs to cite ENCODE data, create bibliography entries, write acknowledgment sections, or ensure compliance with ENCODE data use policy.
Guide for annotating ENCODE regulatory variants with ClinVar clinical significance. Use when users need to check if variants in ENCODE peaks have clinical associations, find pathogenic variants in regulatory regions, or assess variant clinical impact. Trigger on: ClinVar, clinica
Compare ENCODE experiments across different biosamples, tissues, or cell lines to identify tissue-specific regulatory patterns. Use when the user wants cross-tissue comparison, cell-type comparison, tissue-specific elements, differential chromatin, biosample matching, disease vs
Cross-reference ENCODE data with PubMed, bioRxiv, ClinicalTrials.gov, Open Targets, GTEx, ClinVar, GWAS Catalog, gnomAD, Ensembl, and other scientific databases. Use when the user wants to find publications, preprints, or clinical trials related to ENCODE experiments, chain ENCOD
Use ENCODE functional genomics data for disease mechanism research. Use when the user wants to connect GWAS variants to regulatory elements, annotate disease-associated loci with functional data, identify therapeutic targets from epigenomic data, build disease regulatory models,
Download ENCODE genomics files (BED, FASTQ, BAM, bigWig, etc.) to the user's machine. Use when the user wants to download data files from ENCODE experiments.
Every VM came back. The cluster did not. Declarative systems converge on config, and the datapath isn't config.
A surprising share of AI-in-the-terminal failures aren't the AI. They're zsh, and a version of bash from 2006.
A Claude Code plugin turns standalone project configuration into a namespaced, installable extension that teams and communities can update as one unit.
None of the safety came from the model. It came from six boring habits.
Skills package instructions and references. Subagents run work in a separate context and return results. They solve different problems and can be composed deliberately.
Six hours in, one step left, everything green, and the incident that didn't happen
CLAUDE.md carries persistent project context. Skills load reusable procedures when relevant. Separating stable facts from task-specific workflows keeps both easier to maintain.
Twenty minutes recovering secrets that never existed, and the one sentence from a human that ended it
An API request routing a model's tool call through an approval gate to a remote MCP server
31 config keys, two audits, and why the first one was wrong in both directions
The official MCP Registry stores standardized server metadata rather than package code. Publishers verify a namespace, describe installation or remote access, and submit immutable versions.
Everyone looks at the Dockerfile. The file that actually leaked the key was the project file.
Remote MCP authorization uses established OAuth standards, but secure integration still requires issuer validation, least-privilege scopes, protected token handling, and server-side enforcement.
"Copy it over and switch the reference" is two steps, and the outage lives in the one nobody checks
stdio fits local processes and prototypes. Streamable HTTP fits hosted services and shared integrations. The right choice follows where the capability runs and who must reach it.
The most important rule wasn't about what I could change. It was about what I was allowed to display.
Tools perform operations, resources expose readable context, and prompts provide reusable templates. Choosing the correct primitive makes an MCP server easier to understand and govern.
Use MCP Inspector to connect to local or remote servers, inspect capabilities, call tools, read resources, test prompts, and diagnose failures before release.
Build an MCP server in TypeScript with focused tools, validated schemas, local and remote transports, Inspector tests, and production security controls.
An MCP server exposes tools, resources, or prompts through a standard protocol so an AI application can discover and use external capabilities.
/index
Index
Rebuild the index
/ingest-chats
Ingest chats
Import an exported chat history
/ingest-highlights
Ingest highlights
Ingest book or article highlights
/ingest-mine
Ingest mine
Ingest your own finished work
/ingest-newsletter
Ingest newsletter
Ingest newsletters without duplicating
/ingest-paper
Ingest paper
Ingest an academic paper
/ingest-pdf
Ingest pdf
Ingest a PDF
/ingest-url
Ingest url
Clip and ingest a web page
/ingest-voice
Ingest voice
Ingest a voice note
/ingest-youtube
Ingest youtube
Ingest a video or podcast transcript
/ingest
Ingest
Ingest new material from raw/ into the wiki
/init
Init
Scaffold a new vault
/install
Install
Install the skills, commands and agents
/know
Know
What do I know about a topic
/link
Link
Find and add missing connections
/lint
Lint
Audit structure and repair what is mechanical
/merge
Merge
Merge two pages
/metrics
Metrics
Record a dated metrics snapshot
/monthly
Monthly
The monthly structural review
/orphans
Orphans
Find unreachable pages
MCP server for reusable prompt templates, multi-step workflow chains, and quality gates. Compose agentic workflows with an operator syntax; export as native ski…
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