LLM Mart Basic

Analyze Hacker News thread sentiment from a provided HN thread URL.

Automates browser interactions for web testing, form filling, screenshots, and data extraction. Use when the user needs to navigate websites, interact with web pages, fill forms, take screenshots, test web applications, or extract information from web pages.

Write clean, readable Pythonic code. Use this skill any time you write or change a Python file.

Predict protein 3D structures with AlphaFold2 via ColabFold — MMseqs2-accelerated MSAs, monomer and AlphaFold2-Multimer complex folding, and confidence-based validation (pLDDT, pTM/ipTM, PAE). Use when folding a protein sequence or complex from FASTA, generating a predicted struc

Build, slice, concatenate, read, and write AnnData annotated data matrices (obs, var, X, layers, obsm, uns) — the scverse data STRUCTURE, not an analysis pipeline. Use when creating or wrangling .h5ad/zarr files, managing cell and gene annotations, concatenating batches, or handl

Infer gene regulatory networks (GRNs) from expression matrices using arboreto's scalable GRNBoost2 and GENIE3 tree-ensemble algorithms with Dask-distributed computation. Use when analyzing bulk or single-cell RNA-seq transcriptomics to map transcription-factor-to-target-gene regu

Manipulate biological sequences, parse FASTA/GenBank/PDB files, run phylogenetics, and access NCBI/PubMed programmatically via Biopython (Bio.SeqIO, Bio.Entrez, Bio.PDB, Bio.Blast). Use when scripting custom bioinformatics pipelines, batch-processing sequence files, automating BL

Query 40+ bioinformatics web services through one consistent Python API with bioservices (UniProt, KEGG, ChEMBL, Reactome, Ensembl, NCBI and more). Use when a workflow must hit multiple databases together, map identifiers across services, or run cross-database analyses — for quic

Runs NCBI BLAST+ 2.17.0 sequence searches from the command line: makeblastdb (with -parse_seqids), blastn/blastp/blastx/tblastn with tabular -outfmt 6/7 for parsing, correct -task choice (megablast vs blastn vs blastn-short), -taxids/-negative_taxids taxonomic scoping, and -mt_mo

Co-fold biomolecular complexes with Boltz-2, an open AlphaFold3-style model — predict protein + ligand (SMILES/CCD), protein + nucleic-acid, and multi-chain structures in one pass, with binding-affinity prediction. Use when folding a protein together with a small-molecule ligand,

Predict genome-wide functional genomics tracks from DNA sequence with Borzoi (Linder 2025) — a sequence-to-function model outputting RNA-seq, CAGE, ATAC, and ChIP coverage across long context, used to score non-coding and regulatory variant effects. Use when predicting functional

Query the CZ CELLxGENE Census (200M+ cells) programmatically via cellxgene-census and TileDB-SOMA, slicing expression by tissue, disease, or cell type and returning AnnData. Use when pulling reference single-cell RNA-seq data from the largest curated public atlas, running populat

Predict biomolecular complexes with Chai-1, an open AlphaFold3-style model that folds multi-entity assemblies (proteins, ligands, nucleic acids) from a single typed FASTA — strong on antibody–antigen and protein–ligand complexes, with optional MSA and restraint inputs. Use when p

Build and analyze genome-scale constraint-based metabolic models with COBRApy — flux balance analysis (FBA), flux variability analysis (FVA), gene and reaction knockouts, flux sampling, and SBML model I/O. Use when simulating metabolic networks, predicting growth or knockout phen

Process and visualize deep-sequencing coverage with the deepTools CLI — convert BAM to bigWig (bamCoverage), build log2 ratio tracks (bamCompare), run QC (multiBamSummary correlation, PCA, plotFingerprint), apply the ATAC-seq Tn5 shift (alignmentSieve --ATACshift), and make TSS/p

Run ESM protein language models — ESMC for embeddings and representations, ESMFold2 for structure prediction, and ESM3 for generative multimodal protein design across sequence, structure, and function — locally or through the hosted Biohub Platform API (formerly Forge). Use when

Manipulate, annotate, and render phylogenetic trees programmatically with the ETE Toolkit (ete3) — parse and edit Newick/NHX, detect duplication/speciation events, infer orthology and paralogy, query NCBI taxonomy, and export PDF/SVG figures. Use when traversing or reformatting t

Parse and write FCS (Flow Cytometry Standard) files v2.0-3.1 with FlowIO — extract event data as NumPy arrays, read $-keyword metadata and channel/parameter definitions, and convert events to CSV or pandas DataFrame. Use when loading raw .fcs flow-cytometry files, inspecting chan

Run fast one-liner queries to 20+ bioinformatics databases from the gget CLI or Python — gene info (Ensembl), BLAST, AlphaFold structures, Enrichr enrichment, and more. Use for quick interactive lookups of genes, sequences, structures, or pathways — for batch processing or advanc

Analyze and engineer protein glycosylation — scan sequences for N-glycosylation sequons (N-X-S/T), predict O-glycosylation hotspots, and reach curated glycoengineering tools (NetOGlyc, GlycoShield, GlycoWorkbench). Use when identifying or designing glycosylation sites, optimizing

Fourteen posts of being wrong in production, compressed to checkboxes

Healthy nodes, a quiet network, 300 restarts in three days, and a latency budget measured in milliseconds

Discovery worked. Ping worked. Every TCP connection timed out, and later the tunnel only worked when someone had a terminal open.

Every VM came back. The cluster did not. Declarative systems converge on config, and the datapath isn't config.

A surprising share of AI-in-the-terminal failures aren't the AI. They're zsh, and a version of bash from 2006.

A Claude Code plugin turns standalone project configuration into a namespaced, installable extension that teams and communities can update as one unit.

None of the safety came from the model. It came from six boring habits.

Skills package instructions and references. Subagents run work in a separate context and return results. They solve different problems and can be composed deliberately.

Six hours in, one step left, everything green, and the incident that didn't happen

CLAUDE.md carries persistent project context. Skills load reusable procedures when relevant. Separating stable facts from task-specific workflows keeps both easier to maintain.

Twenty minutes recovering secrets that never existed, and the one sentence from a human that ended it

An API request routing a model's tool call through an approval gate to a remote MCP server

31 config keys, two audits, and why the first one was wrong in both directions

The official MCP Registry stores standardized server metadata rather than package code. Publishers verify a namespace, describe installation or remote access, and submit immutable versions.

Everyone looks at the Dockerfile. The file that actually leaked the key was the project file.

Remote MCP authorization uses established OAuth standards, but secure integration still requires issuer validation, least-privilege scopes, protected token handling, and server-side enforcement.

"Copy it over and switch the reference" is two steps, and the outage lives in the one nobody checks

stdio fits local processes and prototypes. Streamable HTTP fits hosted services and shared integrations. The right choice follows where the capability runs and who must reach it.

The most important rule wasn't about what I could change. It was about what I was allowed to display.

Tools perform operations, resources expose readable context, and prompts provide reusable templates. Choosing the correct primitive makes an MCP server easier to understand and govern.

Apply a reusable lesson to ~/.agentskills (rules/skills/templates/commands), backup + commit + push

Generate a quarterly vendor secret-rotation calendar for all load-bearing vendors; emit .ics + ROTATIONS-DUE-NEXT-30-DAYS table; optionally create Google Calendar events

Resolve a 3CX contact or extension by email, extension, or name

Quick health check for a connected 3CX PBX

Snapshot of 3CX queue staffing and active call load

Review and triage abuse mailbox cases in Abnormal Security

Search for specific threat patterns in Abnormal Security by sender, recipient, attack type, or keywords

Triage recent email threats detected by Abnormal Security by severity and attack type

List open and overdue Alternative Payments invoices and optionally generate hosted payment links for them

Reconcile an Alternative Payments payout by listing its transactions and matching them against invoices and customers

EOL/EOS risk report — devices, OS versions, and firmware approaching or past end-of-life/end-of-support, prioritized by criticality

Forward-looking hardware refresh calendar for the given window — replace-now / plan-this-year / monitor tiers

Warranty status snapshot — expired, expiring-soon, and unknown-coverage devices for one client or the whole portfolio

Create a threshold-based monitor for an Atera agent

Create a new service ticket in Atera

Search the Atera knowledge base for articles

List active RMM alerts from Atera

Log work hours on an Atera ticket

Resolve an RMM alert in Atera

Execute a PowerShell script on an Atera agent

Unofficial KakaoTalk CLI and native MCP server for macOS — read, watch, and send messages via Accessibility automation.

Local-first AI action assistant for operators: memory, skills, tools, and permission gates to turn work into controlled action.

Agent-driven media library for your cloud drives (Quark 夸克 / 115 / 光鸭 GuangYa / 123网盘 / 天翼 Tianyi)

An open-source desktop AI agent built around Cyrene’s persona and powered by the self-developed Cyrene_Harness framework. It combines immersive character chat w…

在 Android 上运行的 AI 编程 Agent，内置 Linux 终端与代码编辑器，支持 MCP 协议扩展。

TencentDB Agent Memory is a team-level memory hub for AI Agents — turning conversations, docs, and code into four reusable memory assets (Chat Memory, Skill, LL…

Floe — a native iOS/iPadOS AI agent workspace for iPhone and iPad, built for private bring-your-own-key workflows.

Spring Boot AI Agent — an out-of-the-box solution that makes your app converse, remember, think, and act.

Give your AI agent eyes for PDFs — structured text, tables, OCR, visual evidence, and page-level citations via MCP. Native Rust, local-first.

A tiny Claude Code skill that keeps your prompt cache warm during idle sessions, so your next message reads from cache instead of paying full price.

Monet — Multi-engine mission control for coding agents (Claude Code and Codex today). Browse, search, and drive your agent sessions from a native desktop app.

A DottedSign MCP server that enables AI assistants (Claude, ChatGPT) to manage signing tasks, templates, and document status via natural language.

Курируемый handbook по Claude Code на русском: hooks, skills, CLAUDE.md шаблоны, MCP-серверы, кейсы.

👾 Open Computer Use – Open-Source Alternative to Codex Computer Use

An open-source AI companion that actually remembers you — runs entirely on your own Mac or server. Desktop pet · long-term memory · proactive companionship · mu…

Graphical management tool for Kubernetes on desktop and mobile.

Open-source desktop app for content creation, with an agent runtime and standalone CLI.

Connect Claude and ChatGPT to KDAN PDF — upload, edit, compress, protect, redact, and compare PDFs in chat.

Ekko Studio is a local-first AI workspace for multi-agent chat, coding, and visual workflows, available on desktop and the web.

Open-source native iPhone/iPad client for OpenAI Codex CLI and Claude Code — review diffs, approve actions, steer sessions, and manage Git remotely.