LLM Mart Basic

Run RNA velocity analysis with scVelo on single-cell RNA-seq data — estimate cell-state transitions from spliced/unspliced mRNA dynamics, infer trajectory direction, compute latent time, and identify driver genes. Use when adding directionality to trajectories or studying differe

Train deep generative models for single-cell omics with scvi-tools — probabilistic batch correction and integration (scVI), reference-mapping transfer learning (scArches), differential expression with uncertainty, and multimodal models (totalVI for CITE-seq, MultiVI for multiome)

Analyzes spatial transcriptomics with squidpy (1.8.x) on AnnData and SpatialData objects, routing platforms correctly: Visium spots use spatial_neighbors(coord_type='grid') and pair with deconvolution, while Xenium/MERFISH single-cell data use coord_type='generic'/Delaunay neighb

Store and query genomic variant data at scale with TileDB-VCF — ingest VCF/BCF into compressed TileDB arrays, add samples incrementally, run fast parallel region/sample queries, and export back to VCF. Use when managing population-genomics variant datasets that are too large for

Wraps RDKit in a high-level, pandas-friendly datamol interface with sensible defaults for everyday drug discovery — SMILES/SDF loading into DataFrames, molecule standardization, descriptors, fingerprints, Butina clustering, 3D conformer generation, scaffold analysis, and parallel

Runs molecular machine learning with DeepChem — diverse featurizers, pre-built MoleculeNet benchmark datasets, and pre-trained models (ChemBERTa, GROVER) for property prediction (ADMET, toxicity, solubility) via traditional ML or graph neural networks. Use when running end-to-end

Predicts protein-ligand binding poses with DiffDock diffusion-based molecular docking from PDB structures and SMILES, producing pose confidence scores for virtual screening and structure-based drug design. Use when docking ligands into a protein, generating binding poses, or scre

Computes mass-spectral similarity and identifies compounds for metabolomics with matchms — comparing mass spectra, scoring similarity (cosine, modified cosine), and searching spectral libraries to annotate unknowns. Use when matching MS/MS spectra, identifying metabolites, or lib

Applies medicinal-chemistry filters with the medchem library — drug-likeness rules (Lipinski, Veber), PAINS filters, structural alerts, and molecular complexity metrics for compound prioritization and library cleanup. Use when filtering or triaging a compound library, flagging PA

Featurizes molecules for machine learning with molfeat — ECFP/MACCS/MAP4 fingerprints, RDKit and Mordred physicochemical descriptors, pharmacophore and shape descriptors, and pretrained embeddings (ChemBERTa, ChemGPT, CheMeleon) exposed as scikit-learn transformers that convert S

Queries the Precision Medicine Knowledge Graph (PrimeKG) for multiscale biomedical relationships across genes, drugs, diseases, phenotypes, pathways, and biological processes. Use when exploring drug-disease or gene-disease links, building disease-centric knowledge subgraphs, or

Loads Therapeutics Data Commons (TDC, PyTDC) AI-ready drug-discovery datasets and benchmarks — ADME, toxicity, drug-target interaction (DTI), scaffold splits, and molecular oracles for therapeutic ML and pharmacological prediction. Use when fetching a standardized benchmark datas

Provides the RDKit cheminformatics toolkit for low-level, fine-grained molecular primitives — SMILES/SDF parsing, descriptors (MW, LogP, TPSA), fingerprints, substructure/SMARTS search, 2D/3D coordinate generation, similarity, and reaction handling. Use when custom sanitization,

Drives the Rowan cloud quantum-chemistry platform via its Python API for computational chemistry — pKa prediction, geometry optimization, conformer searching, molecular property calculations, protein-ligand docking (AutoDock Vina), and AI protein cofolding (Chai-1, Boltz-1/2), wi

Builds PyTorch-native graph neural networks with TorchDrug for molecules and proteins, exposing custom GNN architectures, task/dataset abstractions, molecular generation, retrosynthesis planning, and knowledge-graph reasoning. Use when a project specifically needs TorchDrug's dat

Generates professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings — biomarker-stratified patient cohort analyses with outcomes and evidence-based treatment recommendation reports with decision algorithms, supporting GRADE evidence

Prepares ISO 13485 certification documentation for medical device Quality Management Systems (QMS) — gap analysis of existing documentation, Quality Manuals, required procedures and work instructions, and Medical Device Files. Use for ISO 13485 QMS documentation, conducting a doc

Processes and analyzes physiological biosignals with the NeuroKit2 Python toolkit — ECG, EEG, EDA, RSP, PPG, EMG, and EOG signals. Use when processing cardiovascular signals, brain activity, electrodermal responses, respiratory patterns, muscle activity, or eye movements, or when

Reads, writes, and manipulates DICOM (Digital Imaging and Communications in Medicine) medical imaging files with the pydicom Python library. Use when reading/writing/modifying DICOM data, extracting pixel data from CT, MRI, X-ray, or ultrasound images, anonymizing DICOM files, wo

Develops, tests, and validates clinical machine learning models with the PyHealth 2.x healthcare AI toolkit. Use when working with electronic health records (EHR), clinical prediction tasks (mortality, readmission, length of stay, drug recommendation), medical coding systems (ICD

Healthy nodes, a quiet network, 300 restarts in three days, and a latency budget measured in milliseconds

Discovery worked. Ping worked. Every TCP connection timed out, and later the tunnel only worked when someone had a terminal open.

Every VM came back. The cluster did not. Declarative systems converge on config, and the datapath isn't config.

A surprising share of AI-in-the-terminal failures aren't the AI. They're zsh, and a version of bash from 2006.

A Claude Code plugin turns standalone project configuration into a namespaced, installable extension that teams and communities can update as one unit.

None of the safety came from the model. It came from six boring habits.

Skills package instructions and references. Subagents run work in a separate context and return results. They solve different problems and can be composed deliberately.

Six hours in, one step left, everything green, and the incident that didn't happen

CLAUDE.md carries persistent project context. Skills load reusable procedures when relevant. Separating stable facts from task-specific workflows keeps both easier to maintain.

Twenty minutes recovering secrets that never existed, and the one sentence from a human that ended it

An API request routing a model's tool call through an approval gate to a remote MCP server

31 config keys, two audits, and why the first one was wrong in both directions

The official MCP Registry stores standardized server metadata rather than package code. Publishers verify a namespace, describe installation or remote access, and submit immutable versions.

Everyone looks at the Dockerfile. The file that actually leaked the key was the project file.

Remote MCP authorization uses established OAuth standards, but secure integration still requires issuer validation, least-privilege scopes, protected token handling, and server-side enforcement.

"Copy it over and switch the reference" is two steps, and the outage lives in the one nobody checks

stdio fits local processes and prototypes. Streamable HTTP fits hosted services and shared integrations. The right choice follows where the capability runs and who must reach it.

The most important rule wasn't about what I could change. It was about what I was allowed to display.

Tools perform operations, resources expose readable context, and prompts provide reusable templates. Choosing the correct primitive makes an MCP server easier to understand and govern.

Use MCP Inspector to connect to local or remote servers, inspect capabilities, call tools, read resources, test prompts, and diagnose failures before release.

Прогнать контроль качества 1С по изменённым файлам и снять блокирующий гейт

Показать состояние гейта качества 1С — какие файлы ждут проверки

Прогнать контроль качества 1С по изменённым файлам и снять гейт

Triage drain over the keyed audit residue recorded in merged pull-request bodies. Enumerates candidates, resolves each one's cited line, and takes one disposition per entry, promote to a tech-debt issue, dismiss, or keep. Never fixes anything. Pass `list` to see live candidates or `why <path>:<line>` to explain one.

Deprecated - use the aegis:brainstorming skill instead

Deprecated - use the aegis:executing-plans skill instead

Deprecated - use the aegis:writing-plans skill instead

Initialize a new camp

Capture an idea, list intents, or promote an intent to a festival

Commit changes with festival traceability metadata

Create a new festival, phase, sequence, or task

List all festivals with their status and completion percentage

Get the next actionable festival task with full context

Show festival progression (in-progress tasks, roadmap, and dependency view)

Show festival progress and current status

Learn about the Festival Methodology (concepts, structure, rules, and workflows)

Validate festival structure and find issues

Turn one sentence of intent into a structured plan, sized correctly and planned through the loop

Initialize a new camp

Capture an idea, list intents, or promote an intent to a festival

Build AI Agents like playing LEGOs. Everything is a Plugin.

The coding agent that answers to you, your model, your machine, your rules.

CI-native agent CLI tool for deterministic pipeline gating.

Local-first cross-platform desktop workspace for Claude Code / agents: multi-agent, Git worktrees, code diffs, skill marketplace, multi-model, Computer Use, tas…

Local-first visual generation runtime and studio for people and coding agents, with reproducible image and video workflows across multiple providers.

A token-efficient MCP server for safe, line-oriented text file editing with partial reads, hash-based conflict detection, and atomic multi-file operations.

Open-source, evidence-driven MCP server for RTL simulation debugging: correlate VCS/Xcelium logs, VCD/FSDB waveforms, SystemVerilog/UVM source, hierarchy, and c…

runs anywhere. uses anything

One macOS app for Claude Code, Codex, and every agent runtime you use — scheduled runs, global hotkey launcher, per-run git worktrees, one review board.

Soul-driven AI agent with permission-hardened tools, token budgets, and multi-channel access. Runs 24/7 from CLI or Telegram.

Email, SMS & phone-call infrastructure for AI agents — send and receive real email and text messages, and place agent-driven outbound voice calls, all programma…

55 MCP tools to drive the Unity Editor from any MCP-compatible AI agent — scenes, GameObjects, prefabs, assets, tests, and builds. OpenClaw gateway included for…

Google Ads MCP + Meta Ads MCP + GA4 in one server for Claude, ChatGPT, Cursor & n8n — 250+ tools, hosted remote MCP, OAuth login, no API keys. By Ryze AI.

Claude Code & Codex 本地 token 追踪 — 状态栏（Codex 业界首创伪 statusline）、GitHub 风格热力图、多模型成本分析。 | Local token tracker for Claude Code & Codex — status line (industry-first…

Empower the Shell to think. Evolve Operations.

🤖 A full-stack Agent Chat Runtime for pre-production validation, built with act, TypeScript, and LangGraph JS combining streaming, multimodal, HITL, and tools…

Cerul — video memory infrastructure for AI products. SDKs, CLI, MCP, and developer integrations.

Stealth headless browser for AI agents — bypass Cloudflare, bot detection, and anti-scraping. Drop-in Puppeteer/Playwright replacement.

Web research for your agents with smart and safe tooling + knowledge store

FuXi is a fast, self-contained AI coding agent that lives in your terminal — edit code, run commands, and drive tools, with cost-aware routing across LLM provid…