LLM Mart Basic

Run RNA velocity analysis with scVelo on single-cell RNA-seq data — estimate cell-state transitions from spliced/unspliced mRNA dynamics, infer trajectory direction, compute latent time, and identify driver genes. Use when adding directionality to trajectories or studying differe

Train deep generative models for single-cell omics with scvi-tools — probabilistic batch correction and integration (scVI), reference-mapping transfer learning (scArches), differential expression with uncertainty, and multimodal models (totalVI for CITE-seq, MultiVI for multiome)

Analyzes spatial transcriptomics with squidpy (1.8.x) on AnnData and SpatialData objects, routing platforms correctly: Visium spots use spatial_neighbors(coord_type='grid') and pair with deconvolution, while Xenium/MERFISH single-cell data use coord_type='generic'/Delaunay neighb

Store and query genomic variant data at scale with TileDB-VCF — ingest VCF/BCF into compressed TileDB arrays, add samples incrementally, run fast parallel region/sample queries, and export back to VCF. Use when managing population-genomics variant datasets that are too large for

Wraps RDKit in a high-level, pandas-friendly datamol interface with sensible defaults for everyday drug discovery — SMILES/SDF loading into DataFrames, molecule standardization, descriptors, fingerprints, Butina clustering, 3D conformer generation, scaffold analysis, and parallel

Runs molecular machine learning with DeepChem — diverse featurizers, pre-built MoleculeNet benchmark datasets, and pre-trained models (ChemBERTa, GROVER) for property prediction (ADMET, toxicity, solubility) via traditional ML or graph neural networks. Use when running end-to-end

Predicts protein-ligand binding poses with DiffDock diffusion-based molecular docking from PDB structures and SMILES, producing pose confidence scores for virtual screening and structure-based drug design. Use when docking ligands into a protein, generating binding poses, or scre

Computes mass-spectral similarity and identifies compounds for metabolomics with matchms — comparing mass spectra, scoring similarity (cosine, modified cosine), and searching spectral libraries to annotate unknowns. Use when matching MS/MS spectra, identifying metabolites, or lib

Applies medicinal-chemistry filters with the medchem library — drug-likeness rules (Lipinski, Veber), PAINS filters, structural alerts, and molecular complexity metrics for compound prioritization and library cleanup. Use when filtering or triaging a compound library, flagging PA

Featurizes molecules for machine learning with molfeat — ECFP/MACCS/MAP4 fingerprints, RDKit and Mordred physicochemical descriptors, pharmacophore and shape descriptors, and pretrained embeddings (ChemBERTa, ChemGPT, CheMeleon) exposed as scikit-learn transformers that convert S

Queries the Precision Medicine Knowledge Graph (PrimeKG) for multiscale biomedical relationships across genes, drugs, diseases, phenotypes, pathways, and biological processes. Use when exploring drug-disease or gene-disease links, building disease-centric knowledge subgraphs, or

Loads Therapeutics Data Commons (TDC, PyTDC) AI-ready drug-discovery datasets and benchmarks — ADME, toxicity, drug-target interaction (DTI), scaffold splits, and molecular oracles for therapeutic ML and pharmacological prediction. Use when fetching a standardized benchmark datas

Provides the RDKit cheminformatics toolkit for low-level, fine-grained molecular primitives — SMILES/SDF parsing, descriptors (MW, LogP, TPSA), fingerprints, substructure/SMARTS search, 2D/3D coordinate generation, similarity, and reaction handling. Use when custom sanitization,

Drives the Rowan cloud quantum-chemistry platform via its Python API for computational chemistry — pKa prediction, geometry optimization, conformer searching, molecular property calculations, protein-ligand docking (AutoDock Vina), and AI protein cofolding (Chai-1, Boltz-1/2), wi

Builds PyTorch-native graph neural networks with TorchDrug for molecules and proteins, exposing custom GNN architectures, task/dataset abstractions, molecular generation, retrosynthesis planning, and knowledge-graph reasoning. Use when a project specifically needs TorchDrug's dat

Generates professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings — biomarker-stratified patient cohort analyses with outcomes and evidence-based treatment recommendation reports with decision algorithms, supporting GRADE evidence

Prepares ISO 13485 certification documentation for medical device Quality Management Systems (QMS) — gap analysis of existing documentation, Quality Manuals, required procedures and work instructions, and Medical Device Files. Use for ISO 13485 QMS documentation, conducting a doc

Processes and analyzes physiological biosignals with the NeuroKit2 Python toolkit — ECG, EEG, EDA, RSP, PPG, EMG, and EOG signals. Use when processing cardiovascular signals, brain activity, electrodermal responses, respiratory patterns, muscle activity, or eye movements, or when

Reads, writes, and manipulates DICOM (Digital Imaging and Communications in Medicine) medical imaging files with the pydicom Python library. Use when reading/writing/modifying DICOM data, extracting pixel data from CT, MRI, X-ray, or ultrasound images, anonymizing DICOM files, wo

Develops, tests, and validates clinical machine learning models with the PyHealth 2.x healthcare AI toolkit. Use when working with electronic health records (EHR), clinical prediction tasks (mortality, readmission, length of stay, drug recommendation), medical coding systems (ICD

Healthy nodes, a quiet network, 300 restarts in three days, and a latency budget measured in milliseconds

Discovery worked. Ping worked. Every TCP connection timed out, and later the tunnel only worked when someone had a terminal open.

Every VM came back. The cluster did not. Declarative systems converge on config, and the datapath isn't config.

A surprising share of AI-in-the-terminal failures aren't the AI. They're zsh, and a version of bash from 2006.

A Claude Code plugin turns standalone project configuration into a namespaced, installable extension that teams and communities can update as one unit.

None of the safety came from the model. It came from six boring habits.

Skills package instructions and references. Subagents run work in a separate context and return results. They solve different problems and can be composed deliberately.

Six hours in, one step left, everything green, and the incident that didn't happen

CLAUDE.md carries persistent project context. Skills load reusable procedures when relevant. Separating stable facts from task-specific workflows keeps both easier to maintain.

Twenty minutes recovering secrets that never existed, and the one sentence from a human that ended it

An API request routing a model's tool call through an approval gate to a remote MCP server

31 config keys, two audits, and why the first one was wrong in both directions

The official MCP Registry stores standardized server metadata rather than package code. Publishers verify a namespace, describe installation or remote access, and submit immutable versions.

Everyone looks at the Dockerfile. The file that actually leaked the key was the project file.

Remote MCP authorization uses established OAuth standards, but secure integration still requires issuer validation, least-privilege scopes, protected token handling, and server-side enforcement.

"Copy it over and switch the reference" is two steps, and the outage lives in the one nobody checks

stdio fits local processes and prototypes. Streamable HTTP fits hosted services and shared integrations. The right choice follows where the capability runs and who must reach it.

The most important rule wasn't about what I could change. It was about what I was allowed to display.

Tools perform operations, resources expose readable context, and prompts provide reusable templates. Choosing the correct primitive makes an MCP server easier to understand and govern.

Use MCP Inspector to connect to local or remote servers, inspect capabilities, call tools, read resources, test prompts, and diagnose failures before release.

Shows status of the Supabase local development stack.

Stops the Supabase local development stack.

Manage vanity subdomains for Supabase projects.

Configure Tavily MCP server credentials

Run Rigor Explore on top of current_research using the current compatible slug.

Run Rigor Reproduce on this repository using the current compatible slug.

Run Rigor Analyze on this repository using the current compatible slug.

Run Rigor Debug on a research repository failure before patching.

Runs the Open Steps install check and reads the result back in plain words. Use it after installing the pack, when a report never appears, or when someone asks whether the install is sound. The script does the checking and sets the exit code. This command reports what the script printed and nothing else.

`crabbox exec` executes a command on a supported existing lease without syncing files,

List the preflight names accepted by this installed Crabbox binary, their

Редакторский аудит русского текста без переписывания

Редактура русского текста с сохранением смысла и голоса автора

Adversarial design critique of the current work — render it, look at it, and argue for rejection. Run after the gates are green, never instead of them.

Run the one-command quality gate and report the real N/N result. Use before claiming any build/review is done.

Interrogate the brief before a line is built — ask only the questions whose answers change the work, and put every unasked decision on the record as a stated assumption.

Scaffold a new design-product project that matches the recommended Claude Code layout (the reference structure). Use when starting a fresh product/app that will be built with this design system.

Pre-release gate — run the full gate, responsive + render checks, then produce the release checklist (README badge/current/changelog). Use before tagging a release.

Run every objective gate this project can prove and report the real N/N. Use before claiming any screen or component is done.

Create API connector tools for AG2 agents with auth handling, pagination, rate limiting, and error mapping

Atom Agent, Open-Source Governed AI Agent Platform for Self-Hosted Automation

The agent engineering intelligence harness, optimized tools, memory system, subagents and mixture of models packages ⚚

Sesori iOS/Android app and the Sesori Bridge CLI — drive Claude, Codex, OpenCode, Cursor, Pi, OMP, Hermes coding sessions from your phone

🧠 RepoBrain (formerly Antigravity) — Give your repo a brain. ChatGPT for your codebase: works in Claude Code, Cursor, Codex, Windsurf & more.

Use ChatGPT (Codex), Claude, and Grok (X Premium) subscriptions as DeepSeek Harness LLM providers — OAuth login in the web UI, no API keys

Latitude is the open-source AI monitoring platform.

Open-source AI browser agent for Chrome and Firefox (monorepo) 🧠

Official Model Studio CLI（阿里云百炼 CLI）built for AI Agent frameworks, exposing models, search, multimodal, and workflow capabilities as structured tool calls.

Curated DeepSeek Harness (DSH) plugins, extensions, tools, skills, clients, runtimes, integrations, and verified references — English and Chinese.

Turn papers, code, and docs into presentation-ready, natively editable PPTX in Codex / Claude Code. Native charts and equations, speaker notes, click-build anim…

Grix : Work with agents like talking to people.

Local First Ai Agent. Optimized for Local Ai models. Long context window. Proper tools callings. Runs privately on your device.

Model Context Protocol server that integrates AgentQL's data extraction capabilities.

AI that ships your tickets.

Metadata-driven CLI for AI Agent Bots — 48 operations across 7 domains, structured JSON envelope I/O, zero interactive prompts.

An open-source, extensible, self-hosted agent workspace with multi-runtime support for Codex, Claude Code, and more, plus reusable local apps for custom interfa…

Open-source Windows desktop client and GUI for DeepSeek Harness — zero-setup installer with Codex, plugins, skills, SSH, mobile remote access, and 11 skins.

The open-source AI workbench for scientific research

DeepSeek-native AI coding agent for your terminal. Engineered around prefix-cache stability — leave it running.

A Fully free agentic browser driver for AI , few tools, full control, real stealth, top-tier token efficiency.