LLM Mart Basic

Run RNA velocity analysis with scVelo on single-cell RNA-seq data — estimate cell-state transitions from spliced/unspliced mRNA dynamics, infer trajectory direction, compute latent time, and identify driver genes. Use when adding directionality to trajectories or studying differe

Train deep generative models for single-cell omics with scvi-tools — probabilistic batch correction and integration (scVI), reference-mapping transfer learning (scArches), differential expression with uncertainty, and multimodal models (totalVI for CITE-seq, MultiVI for multiome)

Analyzes spatial transcriptomics with squidpy (1.8.x) on AnnData and SpatialData objects, routing platforms correctly: Visium spots use spatial_neighbors(coord_type='grid') and pair with deconvolution, while Xenium/MERFISH single-cell data use coord_type='generic'/Delaunay neighb

Store and query genomic variant data at scale with TileDB-VCF — ingest VCF/BCF into compressed TileDB arrays, add samples incrementally, run fast parallel region/sample queries, and export back to VCF. Use when managing population-genomics variant datasets that are too large for

Wraps RDKit in a high-level, pandas-friendly datamol interface with sensible defaults for everyday drug discovery — SMILES/SDF loading into DataFrames, molecule standardization, descriptors, fingerprints, Butina clustering, 3D conformer generation, scaffold analysis, and parallel

Runs molecular machine learning with DeepChem — diverse featurizers, pre-built MoleculeNet benchmark datasets, and pre-trained models (ChemBERTa, GROVER) for property prediction (ADMET, toxicity, solubility) via traditional ML or graph neural networks. Use when running end-to-end

Predicts protein-ligand binding poses with DiffDock diffusion-based molecular docking from PDB structures and SMILES, producing pose confidence scores for virtual screening and structure-based drug design. Use when docking ligands into a protein, generating binding poses, or scre

Computes mass-spectral similarity and identifies compounds for metabolomics with matchms — comparing mass spectra, scoring similarity (cosine, modified cosine), and searching spectral libraries to annotate unknowns. Use when matching MS/MS spectra, identifying metabolites, or lib

Applies medicinal-chemistry filters with the medchem library — drug-likeness rules (Lipinski, Veber), PAINS filters, structural alerts, and molecular complexity metrics for compound prioritization and library cleanup. Use when filtering or triaging a compound library, flagging PA

Featurizes molecules for machine learning with molfeat — ECFP/MACCS/MAP4 fingerprints, RDKit and Mordred physicochemical descriptors, pharmacophore and shape descriptors, and pretrained embeddings (ChemBERTa, ChemGPT, CheMeleon) exposed as scikit-learn transformers that convert S

Queries the Precision Medicine Knowledge Graph (PrimeKG) for multiscale biomedical relationships across genes, drugs, diseases, phenotypes, pathways, and biological processes. Use when exploring drug-disease or gene-disease links, building disease-centric knowledge subgraphs, or

Loads Therapeutics Data Commons (TDC, PyTDC) AI-ready drug-discovery datasets and benchmarks — ADME, toxicity, drug-target interaction (DTI), scaffold splits, and molecular oracles for therapeutic ML and pharmacological prediction. Use when fetching a standardized benchmark datas

Provides the RDKit cheminformatics toolkit for low-level, fine-grained molecular primitives — SMILES/SDF parsing, descriptors (MW, LogP, TPSA), fingerprints, substructure/SMARTS search, 2D/3D coordinate generation, similarity, and reaction handling. Use when custom sanitization,

Drives the Rowan cloud quantum-chemistry platform via its Python API for computational chemistry — pKa prediction, geometry optimization, conformer searching, molecular property calculations, protein-ligand docking (AutoDock Vina), and AI protein cofolding (Chai-1, Boltz-1/2), wi

Builds PyTorch-native graph neural networks with TorchDrug for molecules and proteins, exposing custom GNN architectures, task/dataset abstractions, molecular generation, retrosynthesis planning, and knowledge-graph reasoning. Use when a project specifically needs TorchDrug's dat

Generates professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings — biomarker-stratified patient cohort analyses with outcomes and evidence-based treatment recommendation reports with decision algorithms, supporting GRADE evidence

Prepares ISO 13485 certification documentation for medical device Quality Management Systems (QMS) — gap analysis of existing documentation, Quality Manuals, required procedures and work instructions, and Medical Device Files. Use for ISO 13485 QMS documentation, conducting a doc

Processes and analyzes physiological biosignals with the NeuroKit2 Python toolkit — ECG, EEG, EDA, RSP, PPG, EMG, and EOG signals. Use when processing cardiovascular signals, brain activity, electrodermal responses, respiratory patterns, muscle activity, or eye movements, or when

Reads, writes, and manipulates DICOM (Digital Imaging and Communications in Medicine) medical imaging files with the pydicom Python library. Use when reading/writing/modifying DICOM data, extracting pixel data from CT, MRI, X-ray, or ultrasound images, anonymizing DICOM files, wo

Develops, tests, and validates clinical machine learning models with the PyHealth 2.x healthcare AI toolkit. Use when working with electronic health records (EHR), clinical prediction tasks (mortality, readmission, length of stay, drug recommendation), medical coding systems (ICD

Healthy nodes, a quiet network, 300 restarts in three days, and a latency budget measured in milliseconds

Discovery worked. Ping worked. Every TCP connection timed out, and later the tunnel only worked when someone had a terminal open.

Every VM came back. The cluster did not. Declarative systems converge on config, and the datapath isn't config.

A surprising share of AI-in-the-terminal failures aren't the AI. They're zsh, and a version of bash from 2006.

A Claude Code plugin turns standalone project configuration into a namespaced, installable extension that teams and communities can update as one unit.

None of the safety came from the model. It came from six boring habits.

Skills package instructions and references. Subagents run work in a separate context and return results. They solve different problems and can be composed deliberately.

Six hours in, one step left, everything green, and the incident that didn't happen

CLAUDE.md carries persistent project context. Skills load reusable procedures when relevant. Separating stable facts from task-specific workflows keeps both easier to maintain.

Twenty minutes recovering secrets that never existed, and the one sentence from a human that ended it

An API request routing a model's tool call through an approval gate to a remote MCP server

31 config keys, two audits, and why the first one was wrong in both directions

The official MCP Registry stores standardized server metadata rather than package code. Publishers verify a namespace, describe installation or remote access, and submit immutable versions.

Everyone looks at the Dockerfile. The file that actually leaked the key was the project file.

Remote MCP authorization uses established OAuth standards, but secure integration still requires issuer validation, least-privilege scopes, protected token handling, and server-side enforcement.

"Copy it over and switch the reference" is two steps, and the outage lives in the one nobody checks

stdio fits local processes and prototypes. Streamable HTTP fits hosted services and shared integrations. The right choice follows where the capability runs and who must reach it.

The most important rule wasn't about what I could change. It was about what I was allowed to display.

Tools perform operations, resources expose readable context, and prompts provide reusable templates. Choosing the correct primitive makes an MCP server easier to understand and govern.

Use MCP Inspector to connect to local or remote servers, inspect capabilities, call tools, read resources, test prompts, and diagnose failures before release.

Extract facts from meetings and update your knowledge base — person profiles, chronological log, and index. Use when the user asks "ingest my meetings", "update my knowledge base", "extract facts from meetings", "sync meetings to wiki", "backfill knowledge", or wants their PARA/Obsidian/wiki profiles updated from conversation data.

Health-check your meeting knowledge for contradictions, stale commitments, and decision conflicts. Use when the user asks "any conflicts in my meetings", "check for stale action items", "lint my meetings", "consistency check", "are there contradictions", or wants to audit their decision history.

List recent meetings and voice memos. Use when the user asks "what meetings did I have", "show my recent recordings", "any meetings today", "list my voice memos", or wants an overview of their meeting history. Also use when they need to find a specific meeting by browsing rather than searching.

Act as the user's live meeting sidekick inside the current terminal agent session. Use when the user explicitly asks you, the terminal agent, to watch a meeting, follow the live transcript, answer during the call, offer strategist thoughts, silently watch for risks, or track decisions. Do not use this skill to start or control the separate Minutes Coach HUD; explicit Coach or HUD lifecycle requests belong to minutes-copilot, and an ambiguous request such as "coach me live" requires one short surface clarification.

Self-coaching analysis of your own behavior across meetings — talk-time ratio, filler words, hedging language, monologue length, energy patterns, and (when meetings are tagged via /minutes-tag) what your behavior in winning meetings looks like vs losing ones. Use this whenever the user says "how did I do", "review my last meeting", "mirror", "self-review", "show my patterns", "coach me", "where am I weak", "talk time", "am I improving", "what do I do in meetings I win", "feedback on me", or asks for any kind of personal feedback on their own meeting behavior. This is the rare skill that gives the user a mirror to their own habits — surface it whenever they show curiosity about their own performance, even if they don't use the word "mirror".

Add a note to the current recording or annotate a past meeting. Use whenever the user says "note that", "remember this", "mark this as important", "add a note about", "annotate the meeting", or wants to capture a thought during or after a recording. Plain text input — no markdown needed.

Interactive meeting preparation — builds a relationship brief and talking points before a call. Use when the user says "prep me for my call with", "I'm meeting with X", "prepare me for", "what should I bring up with", "meeting prep", "get ready for my call", or wants to review history with someone before a meeting.

Generate a daily digest of today's policy-authorized meetings and voice memos — key decisions, action items, and themes across available recordings. Use when the user asks "recap my day", "what happened in my meetings today", "daily summary", "what did I discuss today", "any action items from today", or wants a consolidated view of the day's conversations.

Start or stop recording a meeting, call, or voice memo. Use this whenever the user says "record", "start recording", "capture this meeting", "stop recording", "I'm in a meeting", "take notes on this call", or wants to transcribe live audio. Also use when they ask about recording status or want to know if something is being recorded.

Draft user-facing Minutes release notes for a version from the commit range, recent GitHub releases, and the repository release checks. Use when the user asks to write, generate, prepare, revise, or review release notes or a changelog for a Minutes version.

Search past meeting transcripts and voice memos for specific topics, people, decisions, or ideas. Use this whenever the user asks "what did we discuss about X", "find that meeting where we talked about Y", "what did Alex say", "did we decide on", "what was that idea about", or any question that could be answered by searching their meeting history. Also use for "do I have any notes about" or "check my meetings for".

Guided first-time setup for Minutes — download whisper model, create directories, configure audio input. Use when the user says "set up minutes", "install minutes", "first time setup", "configure minutes", "get started with minutes", "how do I start using minutes", or when verify shows missing components.

Lightweight outcome tagging for meetings — won, lost, stalled, great, or noise. Use whenever the user says "tag this meeting", "mark that as a win", "that one was a loss", "tag yesterday's call as stalled", "mark this great", "that meeting was noise", "label that meeting", or any time they describe a meeting outcome in passing. Tagging takes 5 seconds and unlocks /minutes-mirror correlation analysis — the more meetings get tagged, the smarter mirror gets at telling the user what behavior patterns lead to wins. Surface this skill any time the user mentions a meeting result, win, loss, or wasted time.

Verify that Minutes is properly set up and working — model downloaded, mic accessible, directories exist, no stale state. Use when the user says "is minutes working", "check my setup", "verify minutes", "test recording setup", "why isn't minutes working", "minutes health check", or after running setup for the first time.

Analyze a product walkthrough, bug report video, Loom, or ScreenPal using Minutes transcription plus visual review. Use when the user wants a recorded demo or bug clip turned into a durable brief with transcript, key frames, issues, and next steps.

Weekly meeting synthesis — themes, decision arcs, stale commitments, and what deserves your attention next week. Use when the user says "weekly review", "what happened this week", "weekly summary", "recap my week", "any outstanding items", "week in review", or at the end of a work week.

Search agent history or trace code to its original agent session

Perform a non-destructive cross-artifact consistency and quality analysis across spec.md, plan.md, and tasks.md after task generation.

Generate a custom checklist for the current feature based on user requirements.

Identify underspecified areas in the current feature spec by asking up to 5 highly targeted clarification questions and encoding answers back into the spec.

Open-source MCP servers for Latin American commerce — Pix, NF-e, banking, fiscal, logistics, and messaging across Brazil, Mexico, Argentina, Colombia, Chile, an…

pi coding agent in a technicolor web trenchcoat

Open-source AI Search Intelligence Platform — track, analyze, and improve AI visibility, citations, prompts, competitors, and content opportunities across ChatG…

Open-source toolkit for the QVeris capability routing network: CLI, MCP server, Python SDK, skills, and REST API docs for agents to discover, inspect, call, and…

⚡ The Complete X/Twitter Automation Toolkit — Scrapers, MCP server for AI agents (Claude/GPT), CLI, browser scripts. No API fees. Open source. Unfollow people w…

The AI agent that interacts with you in the real world.

Offline Codex Desktop migration for Windows and macOS.

LLM 驱动的多市场股票智能分析系统：多源行情、实时新闻、决策看板与自动推送，支持零成本定时运行。 LLM-powered multi-market stock analysis system with multi-source market data, real-time news, decision dashbo…

Your smart, reliable, and friendly personal AI assistant.

The LLM Anti-Framework

A general-purpose AIGC video engine: script to finished film in one pipeline — dramas, ads, product videos, otome games, and more. | 通用 AIGC 视频引擎 —— 从剧本到成片一条流水线…

GTM agent for technical founders. Pay-per-result. Signed receipts. Two surfaces: terminal CLI + local web dashboard.

Desktop automation MCP server — computer use for any AI agent: control screen, windows, mouse/keyboard, and Chrome via Model Context Protocol (stdio)

DeepSeek Harness (dsh) Windows desktop client - bundled Node.js + dsh CLI, one-click launch

Open-source, real-time collaborative AI canvas - notes, mini-apps, and agents on one infinite board.

MCPSafari: Native Safari MCP Server for AI Agents

197 bioinformatics & life science skills for Claude Code and AI agents — BixBench 92.0% accuracy. RNA-seq, single-cell, drug discovery, proteomics, and more. Po…

The AI agent with a wallet — spends USDC autonomously to get real work done. Apache-2.0, TypeScript.

The fastest browser for AI agents to run browser automation, built for sharing your logged-in browser state with your AI agents, like Codex or Claude Code, with…

Ouroboros — self-creating AI agent. Born Feb 16, 2026.