LLM Mart Basic

Run full computational-pathology workflows with PathML — whole-slide-image (WSI) analysis across 160+ slide formats, multiplexed immunofluorescence (CODEX, Vectra, MERFISH), nucleus segmentation/classification (HoVer-Net, HACTNet), tissue- and cell-graph construction, HDF5 datase

Build phylogenetic trees end-to-end from raw sequences — MAFFT multiple sequence alignment, optional TrimAl trimming, IQ-TREE 3 maximum-likelihood inference with model selection and bootstraps, FastTree for large datasets, then visualize with ETE3 or FigTree. Use when reconstruct

Design protein sequences for a fixed backbone with ProteinMPNN (Dauparas 2022) — message-passing inverse folding that outputs sequences predicted to fold to a given structure, with fixed positions, tied/symmetric chains, amino-acid bias, and a soluble-model variant. Use when inve

Run differential gene expression analysis on bulk RNA-seq count matrices with PyDESeq2, the Python port of DESeq2 — size-factor normalization, dispersion estimation, Wald tests, FDR (Benjamini-Hochberg) correction, and volcano/MA plots. Use when identifying differentially express

Build complete mass-spectrometry workflows with pyOpenMS — feature detection, peptide identification, protein quantification, and full LC-MS/MS pipelines across many MS file formats (mzML, mzXML) and algorithms. Use for comprehensive proteomics and MS data processing — for simple

Read and write genomic alignment and variant files in Python with pysam (htslib bindings) — SAM/BAM/CRAM alignments, VCF/BCF variants, and FASTA/FASTQ sequences, plus region extraction and per-base coverage/pileup. Use when scripting NGS data-processing pipelines that parse, filt

Runs 16S/ITS amplicon (microbiome) analysis with the QIIME 2 distribution (2026.7; the "amplicon" distribution was renamed "qiime2" in 2026.4) in the correct order: manifest import, cutadapt trim-paired primer removal BEFORE dada2 denoise-paired (trunc-len chosen from the demux q

Generate de-novo protein backbones with RFdiffusion (Watson 2023) — a diffusion model for unconditional monomer generation, motif scaffolding, binder design against a target, and symmetric oligomers. Use when generating a new protein backbone from scratch, scaffolding a functiona

Quantifies bulk RNA-seq transcript abundance with salmon 2.x (the Rust rewrite; selective alignment or --sketch) and kallisto (v0.52.0, kb-python workflow), builds a decoy-aware gentrome index, runs quant with --gcBias -l A, then imports estimates via tximport/tximeta with a tx2g

Run the standard single-cell RNA-seq analysis pipeline with Scanpy on AnnData — QC filtering, normalization, dimensionality reduction (PCA, UMAP, t-SNE), Leiden/Louvain clustering, marker/differential expression, PAGA trajectories, and plotting. Use when analyzing scRNA-seq data

Apply the scGPT single-cell foundation model (Cui 2024) to annotate and embed cells — zero-shot and fine-tuned cell-type annotation, gene/cell embeddings, batch integration, and gene-regulatory / perturbation inference from AnnData. Use when annotating cell types with a pretraine

Run RNA velocity analysis with scVelo on single-cell RNA-seq data — estimate cell-state transitions from spliced/unspliced mRNA dynamics, infer trajectory direction, compute latent time, and identify driver genes. Use when adding directionality to trajectories or studying differe

Train deep generative models for single-cell omics with scvi-tools — probabilistic batch correction and integration (scVI), reference-mapping transfer learning (scArches), differential expression with uncertainty, and multimodal models (totalVI for CITE-seq, MultiVI for multiome)

Analyzes spatial transcriptomics with squidpy (1.8.x) on AnnData and SpatialData objects, routing platforms correctly: Visium spots use spatial_neighbors(coord_type='grid') and pair with deconvolution, while Xenium/MERFISH single-cell data use coord_type='generic'/Delaunay neighb

Store and query genomic variant data at scale with TileDB-VCF — ingest VCF/BCF into compressed TileDB arrays, add samples incrementally, run fast parallel region/sample queries, and export back to VCF. Use when managing population-genomics variant datasets that are too large for

Wraps RDKit in a high-level, pandas-friendly datamol interface with sensible defaults for everyday drug discovery — SMILES/SDF loading into DataFrames, molecule standardization, descriptors, fingerprints, Butina clustering, 3D conformer generation, scaffold analysis, and parallel

Runs molecular machine learning with DeepChem — diverse featurizers, pre-built MoleculeNet benchmark datasets, and pre-trained models (ChemBERTa, GROVER) for property prediction (ADMET, toxicity, solubility) via traditional ML or graph neural networks. Use when running end-to-end

Predicts protein-ligand binding poses with DiffDock diffusion-based molecular docking from PDB structures and SMILES, producing pose confidence scores for virtual screening and structure-based drug design. Use when docking ligands into a protein, generating binding poses, or scre

Computes mass-spectral similarity and identifies compounds for metabolomics with matchms — comparing mass spectra, scoring similarity (cosine, modified cosine), and searching spectral libraries to annotate unknowns. Use when matching MS/MS spectra, identifying metabolites, or lib

Applies medicinal-chemistry filters with the medchem library — drug-likeness rules (Lipinski, Veber), PAINS filters, structural alerts, and molecular complexity metrics for compound prioritization and library cleanup. Use when filtering or triaging a compound library, flagging PA

Fourteen posts of being wrong in production, compressed to checkboxes

Healthy nodes, a quiet network, 300 restarts in three days, and a latency budget measured in milliseconds

Discovery worked. Ping worked. Every TCP connection timed out, and later the tunnel only worked when someone had a terminal open.

Every VM came back. The cluster did not. Declarative systems converge on config, and the datapath isn't config.

A surprising share of AI-in-the-terminal failures aren't the AI. They're zsh, and a version of bash from 2006.

A Claude Code plugin turns standalone project configuration into a namespaced, installable extension that teams and communities can update as one unit.

None of the safety came from the model. It came from six boring habits.

Skills package instructions and references. Subagents run work in a separate context and return results. They solve different problems and can be composed deliberately.

Six hours in, one step left, everything green, and the incident that didn't happen

CLAUDE.md carries persistent project context. Skills load reusable procedures when relevant. Separating stable facts from task-specific workflows keeps both easier to maintain.

Twenty minutes recovering secrets that never existed, and the one sentence from a human that ended it

An API request routing a model's tool call through an approval gate to a remote MCP server

31 config keys, two audits, and why the first one was wrong in both directions

The official MCP Registry stores standardized server metadata rather than package code. Publishers verify a namespace, describe installation or remote access, and submit immutable versions.

Everyone looks at the Dockerfile. The file that actually leaked the key was the project file.

Remote MCP authorization uses established OAuth standards, but secure integration still requires issuer validation, least-privilege scopes, protected token handling, and server-side enforcement.

"Copy it over and switch the reference" is two steps, and the outage lives in the one nobody checks

stdio fits local processes and prototypes. Streamable HTTP fits hosted services and shared integrations. The right choice follows where the capability runs and who must reach it.

The most important rule wasn't about what I could change. It was about what I was allowed to display.

Tools perform operations, resources expose readable context, and prompts provide reusable templates. Choosing the correct primitive makes an MCP server easier to understand and govern.

Generate requirements from goal and research

Run or re-run research phase for current spec

Smart entry point that detects if you need a new spec or should resume existing

Show all specs and their current status

Switch active spec

Generate implementation tasks from design

Decompose a large feature into multiple dependency-aware specs (epic triage)

Check for or install a verified Tree Ring Memory CLI update without changing installation scope

This directory contains the command implementations for the fast-agent CLI.

They operate it without you.

Promised, measured, accepted. A number nobody signed is claimed, not delivered.

Prepare the meeting. One page from the record.

Find the receipt. A dated line, or it did not happen.

Diagnose trust. Process gap, or they stopped trusting you.

Generate, convert, and maintain animated GitHub-safe Markdown documents with animated SVG diagrams. Covers four SVG patterns (architecture flow, lifecycle loop, field carousel, timeline phases), guided interview for any doc type (README, architecture guide, runbook, API reference, tutorial, RFC, post-mortem, how-it-works, or custom), converting existing plain Markdown, diffing for stale diagrams, quality auditing, local preview, and multi-platform export. Use when asked to "create a README for X", "write an architecture doc", "animate this guide", "convert my doc to animated", "check if my diagrams are stale", or "export my doc for Confluence".

AWS profile management for MCP servers — discover profiles across SSO, Granted, and assumed-role chains, check credential TTL, switch profiles across VS Code and Claude Code MCP configs, and scan AWS Organization accounts.

Structured guidance for AWS CloudFront distributions, WAF web ACLs, Lambda@Edge, CloudFront Functions, Firewall Manager multi-account enforcement, and IAM/IRSA patterns. Covers OAC, cache policies, security headers, managed rule groups, rate limiting, FMS FIRST/MIDDLE/LAST ownership model, and production-ready Terraform generation.

Azure identity (Workload Identity, OIDC, Entra ID), resource tagging, AKS platform patterns, RBAC scoping, and production-readiness review — with Terraform generation.

Design, run, and debug Chaos Engineering experiments on Kubernetes using Litmus Chaos v3 and Chaos Mesh v2. Covers fault injection (pod-delete, network-loss, CPU stress, node-drain), steady-state hypothesis probes, GameDay runbooks, scheduled experiments, DORA feedback loop, and RBAC setup. Use when asked to "inject a pod fault", "run a GameDay", "schedule chaos experiments", or "debug why my ChaosEngine is stuck".

Bootstrap Checkov on a developer laptop, run static or plan-level Terraform security scanning for AWS/Azure/GCP/EKS, resolve private GitHub modules via gh CLI, generate pre-commit hooks, produce multi-format output (cli/json/sarif/junit), and fix violations with AI-generated patches. Use when asked to "scan my Terraform", "run checkov", "check my IaC for security issues", "set up checkov pre-commit", or "fix checkov findings".

Okou connects to the tools your team already uses and does the work — across marketing, sales, engineering, and operations, under your control.

An open-source Digital Worker platform for reliable execution, continuous co-evolution, and building Enterprise AI assets.

A curated list of AI Agent evolution, memory systems, multi-agent architectures, and self-improvement projects. | evomap.ai

A governance harness for AI coding.

DeepSeek Harness 手机版：可直接安装的 Android APK，AI 免 Root 操作手机（Shizuku/root 可选），文件编辑只需所有文件访问权限，前台保活 + AI 通知

Local-first, governed AI agent runtime for Python — embed it in your app, or run it as a CLI or ACP server. Permissions, MCP, memory and audit replay built in.

Orbi — the factory that builds and operates AI software factories. GitHub Issues in, releases and runnable system out

Open-source AI agent harness in native Rust — GUI, CLI, headless, and webapp from one binary. Multi-provider, MCP, skills, plugins, agent teams.

The SDK for browser agents. Interact, search, extract, and fetch any site reliably across the web

Agent-native shopping for extreme value: verifiable same-product price evidence, checkout, orders, delivery, and after-sales.

The extensible power-user platform for Google Antigravity. Adds a native In-App Browser, animated Desktop Pets, revamped Gemini UI, and custom BYOK Gemini Pro k…

Open-source, single-binary, self-hosted AI agent — your models and data stay on your machine. A coding agent on par with Claude Code and a personal assistant li…

Your pocket agent. Local-first AI agents on iOS and Android — real workspaces, tool execution with approvals, and your choice of model (DSH · Claude Code · Code…

Bridge between QQ (SnowLuma OneBot v11) and DeepSeek Harness agents: social simulation, safe MCP tools, slang learning and more.

A 7×6 framework for agent architecture. 28 patterns, each placed at a coordinate, runnable Python code with verified engineering slices from Claude Code, Aider,…

针对 AI 自动化渗透 Agent 的新一代反制蜜罐，通过反向代理将API密饵载入真实业务、反向提示词注入等方式反制自动化渗透 Agent，实现多款主流通用Agent的反制上线控制。

Open-source, local-first AI agent for coding and real work. BYOK models, MCP, skills, plugins, workflows, and private knowledge bases.

A free AI-agent toolbox for Android, 一站式安卓AI Agent工具箱

Google Workspace CLI — one command-line tool for Drive, Gmail, Calendar, Sheets, Docs, Chat, Admin, and more. Dynamically built from Google Discovery Service. I…

Independent, unofficial CLI to edit CapCut and JianYing (剪映) projects — subtitles, timing, speed, volume, templates, cut long-form to shorts. No API needed, rea…