LLM Mart Basic

Install bioinformatics tools for ENCODE data analysis. Covers CLI tools (BWA, STAR, samtools, MACS2), R/Bioconductor packages (DESeq2, Seurat, ChIPseeker), Python packages (Scanpy, deeptools), and Nextflow pipeline infrastructure. Generates conda environments, R install scripts,

Guide for integrating CellxGene Census single-cell data with ENCODE bulk experiments. Use when users need cell-type-specific expression context for ENCODE regulatory data, want to deconvolve bulk ENCODE signals, or validate regulatory elements at single-cell resolution. Trigger o

Generate proper ENCODE citations for publications, grants, and presentations. Use when the user needs to cite ENCODE data, create bibliography entries, write acknowledgment sections, or ensure compliance with ENCODE data use policy.

Guide for annotating ENCODE regulatory variants with ClinVar clinical significance. Use when users need to check if variants in ENCODE peaks have clinical associations, find pathogenic variants in regulatory regions, or assess variant clinical impact. Trigger on: ClinVar, clinica

Compare ENCODE experiments across different biosamples, tissues, or cell lines to identify tissue-specific regulatory patterns. Use when the user wants cross-tissue comparison, cell-type comparison, tissue-specific elements, differential chromatin, biosample matching, disease vs

Cross-reference ENCODE data with PubMed, bioRxiv, ClinicalTrials.gov, Open Targets, GTEx, ClinVar, GWAS Catalog, gnomAD, Ensembl, and other scientific databases. Use when the user wants to find publications, preprints, or clinical trials related to ENCODE experiments, chain ENCOD

Use ENCODE functional genomics data for disease mechanism research. Use when the user wants to connect GWAS variants to regulatory elements, annotate disease-associated loci with functional data, identify therapeutic targets from epigenomic data, build disease regulatory models,

Download ENCODE genomics files (BED, FASTQ, BAM, bigWig, etc.) to the user's machine. Use when the user wants to download data files from ENCODE experiments.

Query the Ensembl REST API for regulatory feature annotations, variant effect prediction (VEP), coordinate liftover, gene lookups, and cross-references. Use when the user needs to annotate variants with VEP (consequence, CADD, REVEL, SpliceAI), check Ensembl Regulatory Build over

Build comprehensive epigenomic profiles for tissues or cell types using ENCODE data. Use when the user wants to characterize chromatin states, assemble histone modification panels, create epigenomic landscapes, run ChromHMM segmentation, identify super-enhancers or bivalent domai

Analyze ENCODE functional genomics screens including CRISPR screens, MPRA (Massively Parallel Reporter Assays), and STARR-seq. Find screen data in ENCODE, process results, identify functional elements, and integrate with epigenomic annotations.

Search, query, and cross-reference NCBI GEO (Gene Expression Omnibus) datasets with ENCODE experiments. Use when the user wants to find GEO accessions for ENCODE experiments, search GEO for complementary datasets, download GEO metadata or series matrices, cross-reference ENCODE a

Query gnomAD (Genome Aggregation Database) for population allele frequencies, gene constraint scores, and variant annotations to interpret ENCODE regulatory variants. Use when the user needs allele frequencies for variants in ENCODE regulatory elements, wants to assess gene const

Guide for integrating GTEx tissue expression data with ENCODE regulatory elements. Use when users need to check if a gene is expressed in a tissue, correlate regulatory elements with expression, or validate ENCODE findings against GTEx. Trigger on: GTEx, tissue expression, gene e

Guide for integrating NHGRI-EBI GWAS Catalog associations with ENCODE regulatory data. Use when users need to find GWAS variants in ENCODE peaks, connect regulatory elements to disease associations, or prioritize functional variants using ENCODE annotations. Trigger on: GWAS, gen

Build comprehensive chromatin contact maps by aggregating Hi-C loop calls (BEDPE) across multiple ENCODE experiments, donors, and labs. Use when the user wants to answer "what regions are in 3D contact in my tissue?" by creating a union catalog of chromatin loops. Handles resolut

Build comprehensive histone mark maps by aggregating narrowPeak data across multiple ENCODE experiments, donors, and labs. Use when the user wants to answer "where is this histone mark present in my tissue?" by combining peak calls from multiple studies into a union peak set with

Plan and execute integrative analysis combining multiple ENCODE experiments for cross-dataset or multi-omic workflows. Use when the user wants to combine experiments, perform cross-dataset comparison, multi-omic integration, peak overlap analysis, differential binding, signal cor

Guide for using JASPAR transcription factor binding profiles with ENCODE ChIP-seq data. Use when users need to find TF binding motifs in ENCODE peaks, validate ChIP-seq targets with known motifs, or scan regulatory regions for TF binding potential. Trigger on: JASPAR, motif datab

Convert genomic coordinates between assembly versions (GRCh37/hg19 to GRCh38/hg38, mm9 to mm10). Guides UCSC liftOver for BED files, CrossMap for VCF/bigWig, and handles unmapped regions with provenance logging.

Discovery worked. Ping worked. Every TCP connection timed out, and later the tunnel only worked when someone had a terminal open.

Every VM came back. The cluster did not. Declarative systems converge on config, and the datapath isn't config.

A surprising share of AI-in-the-terminal failures aren't the AI. They're zsh, and a version of bash from 2006.

A Claude Code plugin turns standalone project configuration into a namespaced, installable extension that teams and communities can update as one unit.

None of the safety came from the model. It came from six boring habits.

Skills package instructions and references. Subagents run work in a separate context and return results. They solve different problems and can be composed deliberately.

Six hours in, one step left, everything green, and the incident that didn't happen

CLAUDE.md carries persistent project context. Skills load reusable procedures when relevant. Separating stable facts from task-specific workflows keeps both easier to maintain.

Twenty minutes recovering secrets that never existed, and the one sentence from a human that ended it

An API request routing a model's tool call through an approval gate to a remote MCP server

31 config keys, two audits, and why the first one was wrong in both directions

The official MCP Registry stores standardized server metadata rather than package code. Publishers verify a namespace, describe installation or remote access, and submit immutable versions.

Everyone looks at the Dockerfile. The file that actually leaked the key was the project file.

Remote MCP authorization uses established OAuth standards, but secure integration still requires issuer validation, least-privilege scopes, protected token handling, and server-side enforcement.

"Copy it over and switch the reference" is two steps, and the outage lives in the one nobody checks

stdio fits local processes and prototypes. Streamable HTTP fits hosted services and shared integrations. The right choice follows where the capability runs and who must reach it.

The most important rule wasn't about what I could change. It was about what I was allowed to display.

Tools perform operations, resources expose readable context, and prompts provide reusable templates. Choosing the correct primitive makes an MCP server easier to understand and govern.

Use MCP Inspector to connect to local or remote servers, inspect capabilities, call tools, read resources, test prompts, and diagnose failures before release.

Build an MCP server in TypeScript with focused tools, validated schemas, local and remote transports, Inspector tests, and production security controls.

Instrument services with structured logging, Prometheus metrics, and OpenTelemetry tracing. Build Grafana dashboards, write Prometheus alerting rules, run k6 load tests, and plan infrastructure capacity.

Generate, test, validate, explain, and debug OPA (Open Policy Agent) Rego policies and Conftest configurations. Covers deny/warn/violation rules, unit tests, regal linting, conftest fmt, namespace design, input shape analysis, and GitHub Actions integration. Use when asked to "write a policy", "test a rego file", "validate policies", "explain this rego", or "why is my policy not firing".

OpenShift SCC diagnosis and hardening, Route TLS patterns, OpenShift GitOps app delivery, and cluster upgrade validation.

Comprehensive PR review across six dimensions — cost impact, environment drift, ownership gaps, SOC 2 compliance, deprecated API / version hygiene, and rollback feasibility. Each mode inspects the diff and current file state, reports findings with severity, and recommends concrete fixes. Use when preparing a PR for merge, conducting a pre-deployment readiness check, or performing a post-merge risk assessment.

Production-readiness preflight check for a directory, repo, or single file. Auto-detects file types (Kubernetes manifests, Terraform, GitHub Actions workflows, Helm values/charts, Flux Kustomizations/HelmReleases, Dockerfiles, shell scripts) and applies type-specific checks across the whole scope. Returns a per-file summary table and aggregated verdict. Use before deploying, merging, or applying a folder of config. For PR diffs spanning multiple files use /platform-skills:pr-review instead. For deep Helm chart work use /platform-skills:helmchart instead.

Apply product thinking to platform work — DevEx audits, friction analysis, RFC/ADR drafting, incident communication, post-mortems, capacity planning, cost optimisation, and platform health review.

Generate renovate.json covering all dependency file types used in a repo, emit a GitHub Actions workflow that validates renovate.json on every PR, or generate a pre-commit hook for local validation.

Detect and respond to in-container threats at the syscall level using Falco (eBPF-based, CNCF, open-source, no license cost). Covers Falco installation on EKS/GKE with eBPF driver, custom rule authoring, alert routing via Falcosidekick, rule debugging, and bridging Falco runtime signals to Kyverno admission enforcement. Use when asked to "detect privilege escalation in containers", "set up runtime threat detection", "write a Falco rule", "route Falco alerts to Slack", or "debug why my Falco rule is not firing".

Secrets strategy, External Secrets Operator scaffolding, Sealed Secrets seal/rotate/backup, rotation runbooks, and Kubernetes-side secrets audit.

Bootstrap and operate a self-improving agent workspace. Scaffolds .learnings/ and memory/ directories, captures errors and learnings during a session, detects recurring patterns, and promotes stable entries to project memory (CLAUDE.md, AGENTS.md, or references/). Also implements the Proactive Agent pillars — WAL protocol, working buffer, SESSION-STATE, daily notes, VBR, VFM scoring, ADL decision logic, heartbeat, and reverse prompting. Use when asked to "remember this lesson", "set up agent memory", "log that error", "promote learnings", "capture session state", or "enable proactive mode".

Scaffold a multi-agent AI setup for any repo. Scans the codebase, interviews the developer, generates agent configs for whichever AI tools the repo uses (Copilot, Claude Code, Cursor, Codex, Windsurf). Use when asked to "set up agents", "scaffold Copilot agents", or "create an AGENTS.md".

Secure the software supply chain from source to running container. Covers Cosign keyless image signing (Sigstore/Rekor), SBOM generation and attestation (Syft), vulnerability scanning with severity gates (Trivy/Grype), SLSA Level 2 provenance, and Kyverno/OPA admission enforcement. All open-source, no license cost. Use when asked to "sign my image", "generate an SBOM", "scan for CVEs", "attest build provenance", "enforce image signatures in Kubernetes", or "implement SLSA".

Runs through the full Terraform validation pipeline — fmt, validate, tflint, security scan — and reviews a module or plan for blast radius, IAM risk, and state impact.

Triages a PR comment — from a bot (Copilot, CI) or a human reviewer. Fetches the comment and diff via gh CLI, classifies it, applies the fix directly to the file if valid, posts a reply on the thread, and resolves it. Run from inside the repo.

Scan container images, filesystems, git repos, and existing SBOMs for CVEs, secrets, and license violations using Trivy. Covers local CLI, CI severity gates with SARIF upload, and continuous monitoring via Trivy Operator (Flux HelmRelease). Use when asked to "scan my image", "check for CVEs", "scan this repo for secrets", "scan an SBOM", or "set up continuous cluster vulnerability monitoring". IaC misconfig → /platform-skills:checkov. Admission posture → /platform-skills:kyverno. Image signing/SBOM generation → /platform-skills:supply-chain.

Audit GitHub Actions workflows, composite actions, Dependabot configs, and pre-commit configs for security findings using zizmor — template injection, credential persistence, unpinned uses, over-broad permissions, impostor commits. Covers local CLI, auto-fix, zizmor.yml policy, severity-based CI gates, SARIF upload, and pre-commit. Use when asked to "audit my workflows", "run zizmor", "is this workflow safe", "check for template injection", "pin my actions", or "set up a zizmor CI gate". Workflow syntax and shell errors → /platform-skills:github-actions (actionlint). IaC misconfig → /platform-skills:checkov. Image and dependency CVEs → /platform-skills:trivy. Keeping SHA pins fresh → /platform-skills:renovate.

반복 작업을 `/이름` 으로 호출. 파일명 = 커맨드 이름(`fix-issue.md` → `/fix-issue`).

이슈 #$ARGUMENTS 를 처리한다(이슈 우선 워크플로):

AGENTS.md 생태계(rules·memory·agents·skills·commands·workflows)의 연결 구조를

이슈/기획서 기준 SDLC 한 사이클(이슈→개발→테스트→검증→PR/MR)을 사람 개입 없이 자동 실행.

PiG (Pi in Go) is a faithful Go port of upstream Pi, the TypeScript codebase behind the Pi coding agent. It is a parity-bound translation, not a rewrite: upstre…

An AI Agent that lives in your pocket. Local-first and privacy focused.

Unofficial skill that teaches coding agents to build with TypeSafe AI's Jev: typed decisions, calibrated confidence, and prior art from 150+ community projects.

Adaptive Test-time Learning and Autonomous Specialization

Prediction-market trading engine — Wang Transform pricing on 291K+ contracts; paper-traded across Kalshi · Polymarket · Solana DFlow (Jito bundles) · 633 tests

Knowledge Management for Humans and Agents

Open-source Claude Cowork / Codex / WorkBuddy alternative — a local-first AI office agent that turns one request into real PPTX, DOCX, XLSX and HTML files. Runs…

DeepAgent Code: AI coding agent with persistent memory and control plane

Awesome Jev — evidence-graded index of TypeSafe System One: SDKs, MCP tools, agents, apps and open models. 20 languages, rebuilt every 2 hours.

CLI for Telegram — agent-friendly, daemon-based, with webhook event push.

AI deep-research agent that turns any question into a cited report: plans searches, reads real sources, verifies evidence. Self-hosted, multi-provider, Docker-r…