LLM Mart Basic

Guide for using JASPAR transcription factor binding profiles with ENCODE ChIP-seq data. Use when users need to find TF binding motifs in ENCODE peaks, validate ChIP-seq targets with known motifs, or scan regulatory regions for TF binding potential. Trigger on: JASPAR, motif datab

Convert genomic coordinates between assembly versions (GRCh37/hg19 to GRCh38/hg38, mm9 to mm10). Guides UCSC liftOver for BED files, CrossMap for VCF/bigWig, and handles unmapped regions with provenance logging.

Build comprehensive DNA methylation maps by aggregating WGBS (Whole Genome Bisulfite Sequencing) data across multiple ENCODE experiments, donors, and labs. Use when the user wants to answer "where is DNA methylated/unmethylated in my tissue?" by combining per-CpG methylation data

Guide for de novo and known motif enrichment analysis of ENCODE ChIP-seq and ATAC-seq peaks using HOMER and MEME Suite. Use when users need to discover TF binding motifs in peaks, validate ChIP-seq targets, or find co-binding partners. Trigger on: motif analysis, HOMER, MEME, de

Integrate multiple ENCODE data types (RNA-seq, ATAC-seq, Histone ChIP-seq, TF ChIP-seq) for a tissue/cell type to build a comprehensive regulatory landscape. Use when the user wants to answer "what are the enhancers, promoters, and regulatory elements active in my tissue, and whi

Guide for annotating ENCODE peaks with genomic features using ChIPseeker and GREAT. Use when users need to assign peaks to genes, determine genomic feature distribution (promoter, intron, intergenic), or perform gene ontology enrichment of peak-associated genes. Trigger on: peak

Execute ENCODE ATAC-seq processing pipeline from FASTQ to peaks and signal tracks. Child of pipeline-guide. Provides stage-by-stage Nextflow execution with Docker containers and cloud deployment. Handles Tn5 transposase offset correction, mitochondrial read removal, and nucleosom

Execute ENCODE ChIP-seq processing pipeline from FASTQ to peaks and signal tracks. Child of pipeline-guide. Provides stage-by-stage Nextflow execution with Docker containers and cloud deployment. Use when users need to process ChIP-seq data following ENCODE standards, run peak ca

Execute CUT&RUN processing pipeline from FASTQ to peaks and signal tracks. Child of pipeline-guide. Provides Nextflow execution with Docker and cloud deployment. Use when processing CUT&RUN or CUT&Tag data, an alternative to ChIP-seq with lower background. Trigger on: CUT&RUN pip

Execute ENCODE DNase-seq pipeline from FASTQ to hotspots and footprints. Child of pipeline-guide. Provides Nextflow execution with Docker and cloud deployment. Use when processing DNase-seq data, calling DNase hypersensitive sites, performing footprinting analysis. Trigger on: DN

Execute ENCODE Hi-C pipeline from FASTQ to contact matrices and loop calls. Child of pipeline-guide. Provides Nextflow execution with Docker and cloud deployment. Use when processing Hi-C data, generating contact matrices, or calling loops. Trigger on: Hi-C pipeline, chromatin co

Execute ENCODE RNA-seq pipeline from FASTQ to gene quantification and signal tracks. Child of pipeline-guide. Provides Nextflow execution with Docker and cloud deployment. Use when processing RNA-seq data with STAR alignment, RSEM/Kallisto quantification, or generating expression

Execute ENCODE Whole Genome Bisulfite Sequencing (WGBS) pipeline from FASTQ to methylation calls. Child of pipeline-guide. Provides Nextflow execution with Docker and cloud deployment. Use when processing WGBS/bisulfite-seq data, calling methylation levels, generating bedMethyl f

Assess the scientific integrity and trustworthiness of publications before relying on their findings. Use this skill whenever evaluating a paper for a workflow, citing a study, building an analysis on published methods, or when a user asks about the reliability of a study. Checks

Evaluate ENCODE experiment quality using standard metrics and audit flags. Use when the user asks about data quality, wants to filter for high-quality experiments, needs to interpret quality metrics (FRiP, NSC, RSC, NRF, IDR, TSS enrichment, fragment size), wants to understand EN

Discover and characterize regulatory elements (enhancers, promoters, silencers, insulators, super-enhancers) using ENCODE data and the cCRE catalog. Use when the user wants to find candidate regulatory elements, identify active enhancers in a tissue, map promoter states, classify

Generate publication-ready methods sections, figure legends, supplementary tables, and data availability statements from ENCODE analysis provenance. Implements the scientific documentation standards requiring complete metadata reporting. Use when the user needs to write methods,

Conduct rigorous cross-study meta-analysis of scRNA-seq data from ENCODE, integrating multiple single-cell transcriptomic datasets for a tissue/cell type. Use when the user wants to answer "what cell types exist in my tissue and what genes define them?" by combining scRNA-seq dat

Search and explore ENCODE Project genomics data. Use when the user wants to find experiments, files, or explore what data is available for specific assays, organs, cell lines, or targets.

Set up the ENCODE Toolkit server connection. Use when the user needs help installing, configuring, or troubleshooting the ENCODE connector.

Fourteen posts of being wrong in production, compressed to checkboxes

Healthy nodes, a quiet network, 300 restarts in three days, and a latency budget measured in milliseconds

Discovery worked. Ping worked. Every TCP connection timed out, and later the tunnel only worked when someone had a terminal open.

Every VM came back. The cluster did not. Declarative systems converge on config, and the datapath isn't config.

A surprising share of AI-in-the-terminal failures aren't the AI. They're zsh, and a version of bash from 2006.

A Claude Code plugin turns standalone project configuration into a namespaced, installable extension that teams and communities can update as one unit.

None of the safety came from the model. It came from six boring habits.

Skills package instructions and references. Subagents run work in a separate context and return results. They solve different problems and can be composed deliberately.

Six hours in, one step left, everything green, and the incident that didn't happen

CLAUDE.md carries persistent project context. Skills load reusable procedures when relevant. Separating stable facts from task-specific workflows keeps both easier to maintain.

Twenty minutes recovering secrets that never existed, and the one sentence from a human that ended it

An API request routing a model's tool call through an approval gate to a remote MCP server

31 config keys, two audits, and why the first one was wrong in both directions

The official MCP Registry stores standardized server metadata rather than package code. Publishers verify a namespace, describe installation or remote access, and submit immutable versions.

Everyone looks at the Dockerfile. The file that actually leaked the key was the project file.

Remote MCP authorization uses established OAuth standards, but secure integration still requires issuer validation, least-privilege scopes, protected token handling, and server-side enforcement.

"Copy it over and switch the reference" is two steps, and the outage lives in the one nobody checks

stdio fits local processes and prototypes. Streamable HTTP fits hosted services and shared integrations. The right choice follows where the capability runs and who must reach it.

The most important rule wasn't about what I could change. It was about what I was allowed to display.

Tools perform operations, resources expose readable context, and prompts provide reusable templates. Choosing the correct primitive makes an MCP server easier to understand and govern.

Show current AutoFile policy and settings

Allow all file creation - full permission to create and modify files

Start autoproc - procedural autonomous workflow (legacy command)

Start autorun - autonomous task execution (legacy command)

Show active session-level pattern blocks and allows

Cache-miss / compaction protection gate (disabled by default)

Reference the supported Claude Code command, skill, plugin, and hook surfaces

Clear all session-level pattern blocks and allows

Emergency stop - immediately halt all autonomous operations

Find existing files only - no new file creation (short for /ar:find)

Find existing files only - prevents new file creation (strictest mode)

Git commit requirements - the 17-step process, short for /ar:commit

Use gemini CLI for any combination of: superior vision for analysis of images, diagrams, screenshots, PDFs, documents, video, and audio; code review with detailed citations and cross-referencing patterns; Google search; and multi-model workflows; all for planning, feedback, and getting unstuck.

Clear all global pattern blocks and allows

Block a command pattern globally (persists across sessions)

Allow a blocked pattern globally (persists across sessions)

Show active global pattern blocks and allows

Start autorun - autonomous task execution (short for /ar:run)

Start autoproc - procedural autonomous workflow (short for /ar:proc)

List every autorun command with what it does, in this harness's spelling

AI coding platform for teams

AI Multi-Agent Framework in .NET

Production-ready code examples for Telnyx AI Communications Infrastructure — Voice AI, SMS, SIP, and IoT APIs

UltraGameStudio - AI coding agent for game development: engine workflows, gameplay code, and asset generation.

🦞 ResearchClawBench: Evaluating AI Agents for Automated Research from Re-Discovery to New-Discovery

The context-aware model router that learns & adapts to your long-horizon coding agent workflows. Lightweight & extensible, works with any harnesses, any models,…

Open-source sandboxes where coding agents build and deploy. Spin up isolated environments where Claude Code, Cursor, and other agents code and deploy software.

Native desktop UI for Claude Code with orchestration, streaming, background agents, and multi-provider support. Built with Tauri + React.

OpenCode mobile client via Telegram: run and monitor AI coding tasks from your phone while everything runs locally on your machine. Scheduled tasks support.

Terminal session manager for AI coding agents. One TUI for Claude, Gemini, OpenCode, Codex, and more.

Exposes internet search tools for use by LLM-backed Assist in Home Assistant

Templates and workflow for generating PRDs, Tech Designs, and MVP and more using LLMs for AI IDEs

Versus Incident is the self-hosted AI SRE agent. It learns what your system normally look like and escalates only what is new or unexpected issues — routing to…

Browser-native side panel for Hermes Agent — connect web context to your local Hermes runtime.

Agentic-friendly CLI generator for APIs: turn Swagger, OpenAPI, and google.api.http protos into single-binary CLIs with catalogs and generated Skills.

Open-source agent platform for Global × China enterprises — wire every system through one agent core. Self-hosted, any LLM.

Official python implementation of UTCP. UTCP is an open standard that lets AI agents call any API directly, without extra middleware.

An agent small enough to run anywhere. A minimal agentic runtime in C — ~380 lines, 54KB binary, ~2MB RAM. A skill file + an LLM + a shell loop, no framework.

AgentiLoop Agent! An Autonomous Agentic Agent for Mac, and exclusive Apple only harnesss. Suppprtd automation, scripting, coding, build anything and more. Power…

微信公众号 AI 运营助手 | 选题、写稿、审稿、排版、配图、发布全流程 Skill，支持 OpenClaw / Claude Code / Cursor / Codex