LLM Mart Basic

Generate proper ENCODE citations for publications, grants, and presentations. Use when the user needs to cite ENCODE data, create bibliography entries, write acknowledgment sections, or ensure compliance with ENCODE data use policy.

Guide for annotating ENCODE regulatory variants with ClinVar clinical significance. Use when users need to check if variants in ENCODE peaks have clinical associations, find pathogenic variants in regulatory regions, or assess variant clinical impact. Trigger on: ClinVar, clinica

Compare ENCODE experiments across different biosamples, tissues, or cell lines to identify tissue-specific regulatory patterns. Use when the user wants cross-tissue comparison, cell-type comparison, tissue-specific elements, differential chromatin, biosample matching, disease vs

Cross-reference ENCODE data with PubMed, bioRxiv, ClinicalTrials.gov, Open Targets, GTEx, ClinVar, GWAS Catalog, gnomAD, Ensembl, and other scientific databases. Use when the user wants to find publications, preprints, or clinical trials related to ENCODE experiments, chain ENCOD

Use ENCODE functional genomics data for disease mechanism research. Use when the user wants to connect GWAS variants to regulatory elements, annotate disease-associated loci with functional data, identify therapeutic targets from epigenomic data, build disease regulatory models,

Download ENCODE genomics files (BED, FASTQ, BAM, bigWig, etc.) to the user's machine. Use when the user wants to download data files from ENCODE experiments.

Query the Ensembl REST API for regulatory feature annotations, variant effect prediction (VEP), coordinate liftover, gene lookups, and cross-references. Use when the user needs to annotate variants with VEP (consequence, CADD, REVEL, SpliceAI), check Ensembl Regulatory Build over

Build comprehensive epigenomic profiles for tissues or cell types using ENCODE data. Use when the user wants to characterize chromatin states, assemble histone modification panels, create epigenomic landscapes, run ChromHMM segmentation, identify super-enhancers or bivalent domai

Analyze ENCODE functional genomics screens including CRISPR screens, MPRA (Massively Parallel Reporter Assays), and STARR-seq. Find screen data in ENCODE, process results, identify functional elements, and integrate with epigenomic annotations.

Search, query, and cross-reference NCBI GEO (Gene Expression Omnibus) datasets with ENCODE experiments. Use when the user wants to find GEO accessions for ENCODE experiments, search GEO for complementary datasets, download GEO metadata or series matrices, cross-reference ENCODE a

Query gnomAD (Genome Aggregation Database) for population allele frequencies, gene constraint scores, and variant annotations to interpret ENCODE regulatory variants. Use when the user needs allele frequencies for variants in ENCODE regulatory elements, wants to assess gene const

Guide for integrating GTEx tissue expression data with ENCODE regulatory elements. Use when users need to check if a gene is expressed in a tissue, correlate regulatory elements with expression, or validate ENCODE findings against GTEx. Trigger on: GTEx, tissue expression, gene e

Guide for integrating NHGRI-EBI GWAS Catalog associations with ENCODE regulatory data. Use when users need to find GWAS variants in ENCODE peaks, connect regulatory elements to disease associations, or prioritize functional variants using ENCODE annotations. Trigger on: GWAS, gen

Build comprehensive chromatin contact maps by aggregating Hi-C loop calls (BEDPE) across multiple ENCODE experiments, donors, and labs. Use when the user wants to answer "what regions are in 3D contact in my tissue?" by creating a union catalog of chromatin loops. Handles resolut

Build comprehensive histone mark maps by aggregating narrowPeak data across multiple ENCODE experiments, donors, and labs. Use when the user wants to answer "where is this histone mark present in my tissue?" by combining peak calls from multiple studies into a union peak set with

Plan and execute integrative analysis combining multiple ENCODE experiments for cross-dataset or multi-omic workflows. Use when the user wants to combine experiments, perform cross-dataset comparison, multi-omic integration, peak overlap analysis, differential binding, signal cor

Guide for using JASPAR transcription factor binding profiles with ENCODE ChIP-seq data. Use when users need to find TF binding motifs in ENCODE peaks, validate ChIP-seq targets with known motifs, or scan regulatory regions for TF binding potential. Trigger on: JASPAR, motif datab

Convert genomic coordinates between assembly versions (GRCh37/hg19 to GRCh38/hg38, mm9 to mm10). Guides UCSC liftOver for BED files, CrossMap for VCF/bigWig, and handles unmapped regions with provenance logging.

Build comprehensive DNA methylation maps by aggregating WGBS (Whole Genome Bisulfite Sequencing) data across multiple ENCODE experiments, donors, and labs. Use when the user wants to answer "where is DNA methylated/unmethylated in my tissue?" by combining per-CpG methylation data

Guide for de novo and known motif enrichment analysis of ENCODE ChIP-seq and ATAC-seq peaks using HOMER and MEME Suite. Use when users need to discover TF binding motifs in peaks, validate ChIP-seq targets, or find co-binding partners. Trigger on: motif analysis, HOMER, MEME, de

Fourteen posts of being wrong in production, compressed to checkboxes

Healthy nodes, a quiet network, 300 restarts in three days, and a latency budget measured in milliseconds

Discovery worked. Ping worked. Every TCP connection timed out, and later the tunnel only worked when someone had a terminal open.

Every VM came back. The cluster did not. Declarative systems converge on config, and the datapath isn't config.

A surprising share of AI-in-the-terminal failures aren't the AI. They're zsh, and a version of bash from 2006.

A Claude Code plugin turns standalone project configuration into a namespaced, installable extension that teams and communities can update as one unit.

None of the safety came from the model. It came from six boring habits.

Skills package instructions and references. Subagents run work in a separate context and return results. They solve different problems and can be composed deliberately.

Six hours in, one step left, everything green, and the incident that didn't happen

CLAUDE.md carries persistent project context. Skills load reusable procedures when relevant. Separating stable facts from task-specific workflows keeps both easier to maintain.

Twenty minutes recovering secrets that never existed, and the one sentence from a human that ended it

An API request routing a model's tool call through an approval gate to a remote MCP server

31 config keys, two audits, and why the first one was wrong in both directions

The official MCP Registry stores standardized server metadata rather than package code. Publishers verify a namespace, describe installation or remote access, and submit immutable versions.

Everyone looks at the Dockerfile. The file that actually leaked the key was the project file.

Remote MCP authorization uses established OAuth standards, but secure integration still requires issuer validation, least-privilege scopes, protected token handling, and server-side enforcement.

"Copy it over and switch the reference" is two steps, and the outage lives in the one nobody checks

stdio fits local processes and prototypes. Streamable HTTP fits hosted services and shared integrations. The right choice follows where the capability runs and who must reach it.

The most important rule wasn't about what I could change. It was about what I was allowed to display.

Tools perform operations, resources expose readable context, and prompts provide reusable templates. Choosing the correct primitive makes an MCP server easier to understand and govern.

Guided component creation with proper patterns

Review existing UI for issues and improvements

Initialize a design system with tokens

Generate unit tests for Python, JavaScript/TypeScript, and React code with mocks, edge cases, and coverage gap analysis

Turn a recorded product demo into a prioritized backlog with timestamped evidence.

Turn one screen recording of a bug into an evidence-backed GitHub issue draft (quote, frames, OCR identifiers, wall-clock; silent recordings work too).

Walk a recording's remarks against system logs using wall-clock timestamps.

Turn a recorded meeting (audio is enough) into action items, decisions, and open questions with timestamps.

Turn a recorded workshop or design walkthrough into a structured spec with quoted decisions and open questions.

Turn a narrated screencast into precise, evidence-backed findings JSON (bug / feature / question routing with frame evidence).

Generate and enforce policy gates for AI coding agents (Copilot, Claude Code) — real-time session hooks that deny protected-path edits and dangerous commands, plus a merge-time backstop for anything that bypasses them. Use when asked to "govern AI agents", "block AI from touching secrets", "add an AI policy gate", or "why did the AI agent hook not fire".

Show the active planning-with-files plan (id, mode, attestation, current phase, phase counts)

Start planning-with-files (task_plan.md, findings.md, progress.md); flags --gated, --autonomous, --template analytics, then an optional plan name

Run a paid-ads (ROAS) workflow: audience segments, account structure, ad creative, experiment design, pre-launch signal QA + the account-audit gate, measurement, and attribution. Not sure? Use /aaron-marketing:auto.

Natural-language front door to the marketing pack (narrative/TALE, SEO/GEO/SITE, social/ECHO, email/SEND, Paid Ads/ROAS, influencer/STAR, launch/RAMP). Use when a marketing goal is open-ended or spans disciplines, when it is unclear which skill fits, or for requests like 'help with our marketing', 'grow our traffic', 'plan our launch', 'what should we post', 'is our messaging landing' — it infers the discipline and runs the smallest useful workflow. Add --deep for exhaustive, maximum-rigor, or stress-test runs.

Run an email-marketing (SEND) workflow: deliverability/consent setup, segmentation, email creative, lifecycle flows, newsletter monetization, send-testing, and the email-quality audit gate. Not sure? Use /aaron-marketing:auto.

Run an influencer-marketing (STAR) workflow: audience & creator scouting, campaign targeting, briefs, outreach, amplification, and ROI reporting. Not sure? Use /aaron-marketing:auto.

Run a product-launch (RAMP) workflow: positioning and launch tiering, window/early-access design, message house and asset kits, the launch-readiness gate with a T-1 go/no-go, launch-day execution, and the post-launch prove loop. Not sure? Use /aaron-marketing:auto.

Run a brand-narrative & messaging (TALE) workflow: trace the current message and positioning truth, architect the durable message house/voice/story canon, land it consistently across every surface, and evaluate resonance with tests and drift monitoring. Not sure? Use /aaron-marketing:auto.

SEO/GEO end-to-end along the SITE loop: survey demand and competitors, implement content, tune quality/tech/on-page, and evaluate authority/rankings/reports/memory (--phase survey|implement|tune|evaluate). Not sure? Use /aaron-marketing:auto.

The fastest way to put Volcengine Ark in your terminal and your AI agent — go from prompt to generated media, multimodal answer, or deployed endpoint in a sin…

本地私有、开源的自进化跨平台 AI 内容发现 Agent：先理解你，再主动从 B站、小红书、抖音、YouTube、X、知乎、Reddit、微博等平台与开放 Web 寻找内容。（支持 deepseek harness 插件） | Local-first open-source cross-platform AI cont…

Persistent memory for AI coding agents — one verified kb_search replaces the grep/find/ls orientation loop. Cross-repo, CPU-only, zero token spend.

AI 时代的伯克希尔：基于 Claude Code / Codex 的价值投资研究框架。巴菲特·芒格·段永平·李录四大师方法论 + 多Agent并行研究。| AI-era Berkshire: a value investing research framework built for Claude Code / Co…

The batteries-included, No-Code FinOps automation platform, with the AI you trust.

Open-source 3D AI agent framework — GLB/glTF avatars with LLM brains, memory, emotions, and autonomous payments. MCP server · x402 · Solana/EVM · Three.js. Embe…

XLSX parser for LLMs, RAG, LangChain, LangGraph, CrewAI, Claude, MCP — turns Excel (.xlsx) into citation-ready JSON with formulas, charts, dependency graphs, an…

Hermes-Relay — Your Hermes AI agent, in your pocket — chat, voice, and control.

A minimalist, terminal-native coding agent written in C.

AI-powered OSINT agent with interactive REPL, MCP server, and CLI. 19 tools. Works with Claude, GPT-4, or local models. For authorized security research only.

AI pair programming in your terminal — one static binary, sub-ms startup, any model

Where data access meets operational intelligence

Build your own security agents. Open-source framework for agents with live, read-only access to your infrastructure, with no path to widen it. Reasons across AW…

Multi-workspace terminal aggregator with Claude Code AI integration

Go implementation of AI coding agent

Harness engineering beginner tutorial, from 0 to 1

Generate images directly in DeepSeek Harness chats

A smarter, self-hosted AI assistant — multi-user, multi-agent.

Turn any research paper into a commercialization report — 6 AI agents, TRL/MRL scoring, patent landscape, market intelligence, verified citations. DeepSeek / Op…

Power BI CLI - semantic models (.NET TOM) and PBIR reports for token-efficient AI agent usage, built for Claude Code