LLM Mart Basic

Runs 16S/ITS amplicon (microbiome) analysis with the QIIME 2 distribution (2026.7; the "amplicon" distribution was renamed "qiime2" in 2026.4) in the correct order: manifest import, cutadapt trim-paired primer removal BEFORE dada2 denoise-paired (trunc-len chosen from the demux q

Generate de-novo protein backbones with RFdiffusion (Watson 2023) — a diffusion model for unconditional monomer generation, motif scaffolding, binder design against a target, and symmetric oligomers. Use when generating a new protein backbone from scratch, scaffolding a functiona

Quantifies bulk RNA-seq transcript abundance with salmon 2.x (the Rust rewrite; selective alignment or --sketch) and kallisto (v0.52.0, kb-python workflow), builds a decoy-aware gentrome index, runs quant with --gcBias -l A, then imports estimates via tximport/tximeta with a tx2g

Run the standard single-cell RNA-seq analysis pipeline with Scanpy on AnnData — QC filtering, normalization, dimensionality reduction (PCA, UMAP, t-SNE), Leiden/Louvain clustering, marker/differential expression, PAGA trajectories, and plotting. Use when analyzing scRNA-seq data

Apply the scGPT single-cell foundation model (Cui 2024) to annotate and embed cells — zero-shot and fine-tuned cell-type annotation, gene/cell embeddings, batch integration, and gene-regulatory / perturbation inference from AnnData. Use when annotating cell types with a pretraine

Run RNA velocity analysis with scVelo on single-cell RNA-seq data — estimate cell-state transitions from spliced/unspliced mRNA dynamics, infer trajectory direction, compute latent time, and identify driver genes. Use when adding directionality to trajectories or studying differe

Train deep generative models for single-cell omics with scvi-tools — probabilistic batch correction and integration (scVI), reference-mapping transfer learning (scArches), differential expression with uncertainty, and multimodal models (totalVI for CITE-seq, MultiVI for multiome)

Analyzes spatial transcriptomics with squidpy (1.8.x) on AnnData and SpatialData objects, routing platforms correctly: Visium spots use spatial_neighbors(coord_type='grid') and pair with deconvolution, while Xenium/MERFISH single-cell data use coord_type='generic'/Delaunay neighb

Store and query genomic variant data at scale with TileDB-VCF — ingest VCF/BCF into compressed TileDB arrays, add samples incrementally, run fast parallel region/sample queries, and export back to VCF. Use when managing population-genomics variant datasets that are too large for

Wraps RDKit in a high-level, pandas-friendly datamol interface with sensible defaults for everyday drug discovery — SMILES/SDF loading into DataFrames, molecule standardization, descriptors, fingerprints, Butina clustering, 3D conformer generation, scaffold analysis, and parallel

Runs molecular machine learning with DeepChem — diverse featurizers, pre-built MoleculeNet benchmark datasets, and pre-trained models (ChemBERTa, GROVER) for property prediction (ADMET, toxicity, solubility) via traditional ML or graph neural networks. Use when running end-to-end

Predicts protein-ligand binding poses with DiffDock diffusion-based molecular docking from PDB structures and SMILES, producing pose confidence scores for virtual screening and structure-based drug design. Use when docking ligands into a protein, generating binding poses, or scre

Computes mass-spectral similarity and identifies compounds for metabolomics with matchms — comparing mass spectra, scoring similarity (cosine, modified cosine), and searching spectral libraries to annotate unknowns. Use when matching MS/MS spectra, identifying metabolites, or lib

Applies medicinal-chemistry filters with the medchem library — drug-likeness rules (Lipinski, Veber), PAINS filters, structural alerts, and molecular complexity metrics for compound prioritization and library cleanup. Use when filtering or triaging a compound library, flagging PA

Featurizes molecules for machine learning with molfeat — ECFP/MACCS/MAP4 fingerprints, RDKit and Mordred physicochemical descriptors, pharmacophore and shape descriptors, and pretrained embeddings (ChemBERTa, ChemGPT, CheMeleon) exposed as scikit-learn transformers that convert S

Queries the Precision Medicine Knowledge Graph (PrimeKG) for multiscale biomedical relationships across genes, drugs, diseases, phenotypes, pathways, and biological processes. Use when exploring drug-disease or gene-disease links, building disease-centric knowledge subgraphs, or

Loads Therapeutics Data Commons (TDC, PyTDC) AI-ready drug-discovery datasets and benchmarks — ADME, toxicity, drug-target interaction (DTI), scaffold splits, and molecular oracles for therapeutic ML and pharmacological prediction. Use when fetching a standardized benchmark datas

Provides the RDKit cheminformatics toolkit for low-level, fine-grained molecular primitives — SMILES/SDF parsing, descriptors (MW, LogP, TPSA), fingerprints, substructure/SMARTS search, 2D/3D coordinate generation, similarity, and reaction handling. Use when custom sanitization,

Drives the Rowan cloud quantum-chemistry platform via its Python API for computational chemistry — pKa prediction, geometry optimization, conformer searching, molecular property calculations, protein-ligand docking (AutoDock Vina), and AI protein cofolding (Chai-1, Boltz-1/2), wi

Builds PyTorch-native graph neural networks with TorchDrug for molecules and proteins, exposing custom GNN architectures, task/dataset abstractions, molecular generation, retrosynthesis planning, and knowledge-graph reasoning. Use when a project specifically needs TorchDrug's dat

A Claude Code plugin turns standalone project configuration into a namespaced, installable extension that teams and communities can update as one unit.

None of the safety came from the model. It came from six boring habits.

Skills package instructions and references. Subagents run work in a separate context and return results. They solve different problems and can be composed deliberately.

Six hours in, one step left, everything green, and the incident that didn't happen

CLAUDE.md carries persistent project context. Skills load reusable procedures when relevant. Separating stable facts from task-specific workflows keeps both easier to maintain.

Twenty minutes recovering secrets that never existed, and the one sentence from a human that ended it

An API request routing a model's tool call through an approval gate to a remote MCP server

31 config keys, two audits, and why the first one was wrong in both directions

The official MCP Registry stores standardized server metadata rather than package code. Publishers verify a namespace, describe installation or remote access, and submit immutable versions.

Everyone looks at the Dockerfile. The file that actually leaked the key was the project file.

Remote MCP authorization uses established OAuth standards, but secure integration still requires issuer validation, least-privilege scopes, protected token handling, and server-side enforcement.

"Copy it over and switch the reference" is two steps, and the outage lives in the one nobody checks

stdio fits local processes and prototypes. Streamable HTTP fits hosted services and shared integrations. The right choice follows where the capability runs and who must reach it.

The most important rule wasn't about what I could change. It was about what I was allowed to display.

Tools perform operations, resources expose readable context, and prompts provide reusable templates. Choosing the correct primitive makes an MCP server easier to understand and govern.

Use MCP Inspector to connect to local or remote servers, inspect capabilities, call tools, read resources, test prompts, and diagnose failures before release.

Build an MCP server in TypeScript with focused tools, validated schemas, local and remote transports, Inspector tests, and production security controls.

An MCP server exposes tools, resources, or prompts through a standard protocol so an AI application can discover and use external capabilities.

Treat an AI agent skill as both an instruction package and a software dependency: inspect what it says, what it runs, what it can access, and how it updates.

Add remote HTTP or local stdio MCP servers to Claude Code, choose the right scope, protect credentials, verify the connection, and test with least privilege.

`crabbox inspect` prints the full record for a single lease: state, provider,

Run named, repo-local jobs defined in your Crabbox config.

`crabbox list` shows the current Crabbox machines (leases) for a provider. It is

`crabbox login` authenticates the CLI against a coordinator, stores the

`crabbox logout` clears the stored broker token from your user config so the CLI

`crabbox logs` prints the retained command output for a recorded run.

`crabbox marketplace` previews the Crabbox credits gateway: one Crabbox billing

`crabbox media` turns a recorded desktop video into lightweight review

`crabbox open` prepares an existing SSH-capable lease for an external editor.

`crabbox pause` pauses a single lease, freeing the remote compute while

`crabbox pond` is the cross-provider peer-discovery and lifecycle surface for a

`crabbox pool` contains machine-pool helpers. `pool list` keeps the older

`crabbox ports` bridges provider-native port publishing for an existing Crabbox

`crabbox prewarm` leases a reusable box and prepares it for test runs. For

`crabbox providers` prints the provider capability matrix that the CLI compiles

`crabbox receipt <run-id>` retrieves a brokered run's committed terminal

`crabbox results` prints the structured test summary attached to a recorded

`crabbox resume` resumes a lease previously paused with [`pause`](pause.md),

`crabbox run` syncs the current dirty checkout to a box, runs a command there,

`crabbox screenshot` captures a single PNG from a desktop lease without opening a

Claude Code skills for Chinese-narration recaps from supported video files, with optional editable JianYing/CapCut draft export. | 用 Claude Code skills 为支持的视频文件…

Drive the Unity Editor from an AI agent or the terminal. The Editor serves MCP itself over HTTP, so there is no second process to run, and the isuzu-unity-cli c…

面向企业的数字员工构建与运行平台：把专业员工的经验、流程与判断标准，固化为可随时上岗、可配置、可审批、可观测的 AI 数字员工。

A local-first, Pi-powered AI agent workspace for Desktop, WebUI, and CLI

660+ muapi-hosted generative-media models plus community-submitted third-party API tools (SEO, enrichment, social, scraping) — one YAML file per entry, browsabl…

A compounding agent OS for recursive agents. Also an open source alternative to Grok Bot and Meta's Muse.

Independent desktop client for OpenCode 2. Manage projects, sessions, parallel agents, requests, and changes on Linux and macOS.

Production agent skills for Claude Code, Cursor, and any SKILL.md harness — Codex fleets, video pipeline, monorepo review bundles, multi-chain explorer.

See and manage what your coding assistants load — skills, commands, subagents, plugins and MCP servers, with real usage.

An Enterprise-Grade Full-Stack RBAC Permission Management System Built with Go + React

Create AI Agents in a No-Code Visual Builder or TypeScript SDK with full 2-way sync. For shipping AI assistants and multi-agent AI workflows.

基于 DeepSeek Harness（DSH）的稳定桌面端，集成Git、内置浏览器与记忆功能 | DeepSeek Harness desktop GUI with local workspaces, Git, browser and memory.

⚡ Control Apache Airflow with natural language via MCP. Chat with your workflows using Claude, GPT, or any LLM — no REST API calls needed. Supports Airflow 2.x…

Open-source CLI, schemas, resolver, and DSH agent tools for DSH Plugin Hub

Pi Coding Agent 中文学习蓝皮书：从安装与第一个可验收任务开始，逐步掌握 Session、Context、Skill、Extension、Subagent 与长期 Agent 工作流。

Self-hosted framework for orchestrating fleets of specialist AI agents — ensemble reasoning and a full agentic coding pipeline, model-agnostic and local-friendl…

Self-hosted, vendor-neutral control plane for your local coding agents (Claude Code & Codex). Run your agents, on any plane.

A practical AI agents handbook covering agent systems, agentic workflows, LangGraph, MCP/A2A, context engineering, agent memory, evaluation, observability, and…

Vibe Coding 从入门到精通教程｜AI 结对编程工作流｜Prompt、Skill、Workflow、上下文管理、codex实战指南

Static security scanner for LLM agents — prompt injection, MCP config auditing, taint analysis. 51 rules mapped to OWASP Agentic Top 10 (2026). Works with LangC…