LLM Mart Basic

Analyze Neuropixels 1.0/2.0 extracellular electrophysiology with SpikeInterface — load SpikeGLX/Open Ephys recordings, preprocess and motion-correct, run Kilosort4 spike sorting, compute quality metrics, apply Allen/IBL curation, and do AI-assisted visual inspection. Use when wor

Runs FASTQ-to-VCF germline and somatic variant calling via the Nextflow nf-core/sarek pipeline pinned to -r 3.10.0 — builds the samplesheet.csv (patient, sex, status, sample, lane, fastq_1, fastq_2), runs bwa-mem/bwa-mem2/dragmap alignment plus GATK4 MarkDuplicates and BQSR again

Run full computational-pathology workflows with PathML — whole-slide-image (WSI) analysis across 160+ slide formats, multiplexed immunofluorescence (CODEX, Vectra, MERFISH), nucleus segmentation/classification (HoVer-Net, HACTNet), tissue- and cell-graph construction, HDF5 datase

Build phylogenetic trees end-to-end from raw sequences — MAFFT multiple sequence alignment, optional TrimAl trimming, IQ-TREE 3 maximum-likelihood inference with model selection and bootstraps, FastTree for large datasets, then visualize with ETE3 or FigTree. Use when reconstruct

Design protein sequences for a fixed backbone with ProteinMPNN (Dauparas 2022) — message-passing inverse folding that outputs sequences predicted to fold to a given structure, with fixed positions, tied/symmetric chains, amino-acid bias, and a soluble-model variant. Use when inve

Run differential gene expression analysis on bulk RNA-seq count matrices with PyDESeq2, the Python port of DESeq2 — size-factor normalization, dispersion estimation, Wald tests, FDR (Benjamini-Hochberg) correction, and volcano/MA plots. Use when identifying differentially express

Build complete mass-spectrometry workflows with pyOpenMS — feature detection, peptide identification, protein quantification, and full LC-MS/MS pipelines across many MS file formats (mzML, mzXML) and algorithms. Use for comprehensive proteomics and MS data processing — for simple

Read and write genomic alignment and variant files in Python with pysam (htslib bindings) — SAM/BAM/CRAM alignments, VCF/BCF variants, and FASTA/FASTQ sequences, plus region extraction and per-base coverage/pileup. Use when scripting NGS data-processing pipelines that parse, filt

Runs 16S/ITS amplicon (microbiome) analysis with the QIIME 2 distribution (2026.7; the "amplicon" distribution was renamed "qiime2" in 2026.4) in the correct order: manifest import, cutadapt trim-paired primer removal BEFORE dada2 denoise-paired (trunc-len chosen from the demux q

Generate de-novo protein backbones with RFdiffusion (Watson 2023) — a diffusion model for unconditional monomer generation, motif scaffolding, binder design against a target, and symmetric oligomers. Use when generating a new protein backbone from scratch, scaffolding a functiona

Quantifies bulk RNA-seq transcript abundance with salmon 2.x (the Rust rewrite; selective alignment or --sketch) and kallisto (v0.52.0, kb-python workflow), builds a decoy-aware gentrome index, runs quant with --gcBias -l A, then imports estimates via tximport/tximeta with a tx2g

Run the standard single-cell RNA-seq analysis pipeline with Scanpy on AnnData — QC filtering, normalization, dimensionality reduction (PCA, UMAP, t-SNE), Leiden/Louvain clustering, marker/differential expression, PAGA trajectories, and plotting. Use when analyzing scRNA-seq data

Apply the scGPT single-cell foundation model (Cui 2024) to annotate and embed cells — zero-shot and fine-tuned cell-type annotation, gene/cell embeddings, batch integration, and gene-regulatory / perturbation inference from AnnData. Use when annotating cell types with a pretraine

Run RNA velocity analysis with scVelo on single-cell RNA-seq data — estimate cell-state transitions from spliced/unspliced mRNA dynamics, infer trajectory direction, compute latent time, and identify driver genes. Use when adding directionality to trajectories or studying differe

Train deep generative models for single-cell omics with scvi-tools — probabilistic batch correction and integration (scVI), reference-mapping transfer learning (scArches), differential expression with uncertainty, and multimodal models (totalVI for CITE-seq, MultiVI for multiome)

Analyzes spatial transcriptomics with squidpy (1.8.x) on AnnData and SpatialData objects, routing platforms correctly: Visium spots use spatial_neighbors(coord_type='grid') and pair with deconvolution, while Xenium/MERFISH single-cell data use coord_type='generic'/Delaunay neighb

Store and query genomic variant data at scale with TileDB-VCF — ingest VCF/BCF into compressed TileDB arrays, add samples incrementally, run fast parallel region/sample queries, and export back to VCF. Use when managing population-genomics variant datasets that are too large for

Wraps RDKit in a high-level, pandas-friendly datamol interface with sensible defaults for everyday drug discovery — SMILES/SDF loading into DataFrames, molecule standardization, descriptors, fingerprints, Butina clustering, 3D conformer generation, scaffold analysis, and parallel

Runs molecular machine learning with DeepChem — diverse featurizers, pre-built MoleculeNet benchmark datasets, and pre-trained models (ChemBERTa, GROVER) for property prediction (ADMET, toxicity, solubility) via traditional ML or graph neural networks. Use when running end-to-end

Predicts protein-ligand binding poses with DiffDock diffusion-based molecular docking from PDB structures and SMILES, producing pose confidence scores for virtual screening and structure-based drug design. Use when docking ligands into a protein, generating binding poses, or scre

Every VM came back. The cluster did not. Declarative systems converge on config, and the datapath isn't config.

A surprising share of AI-in-the-terminal failures aren't the AI. They're zsh, and a version of bash from 2006.

A Claude Code plugin turns standalone project configuration into a namespaced, installable extension that teams and communities can update as one unit.

None of the safety came from the model. It came from six boring habits.

Skills package instructions and references. Subagents run work in a separate context and return results. They solve different problems and can be composed deliberately.

Six hours in, one step left, everything green, and the incident that didn't happen

CLAUDE.md carries persistent project context. Skills load reusable procedures when relevant. Separating stable facts from task-specific workflows keeps both easier to maintain.

Twenty minutes recovering secrets that never existed, and the one sentence from a human that ended it

An API request routing a model's tool call through an approval gate to a remote MCP server

31 config keys, two audits, and why the first one was wrong in both directions

The official MCP Registry stores standardized server metadata rather than package code. Publishers verify a namespace, describe installation or remote access, and submit immutable versions.

Everyone looks at the Dockerfile. The file that actually leaked the key was the project file.

Remote MCP authorization uses established OAuth standards, but secure integration still requires issuer validation, least-privilege scopes, protected token handling, and server-side enforcement.

"Copy it over and switch the reference" is two steps, and the outage lives in the one nobody checks

stdio fits local processes and prototypes. Streamable HTTP fits hosted services and shared integrations. The right choice follows where the capability runs and who must reach it.

The most important rule wasn't about what I could change. It was about what I was allowed to display.

Tools perform operations, resources expose readable context, and prompts provide reusable templates. Choosing the correct primitive makes an MCP server easier to understand and govern.

Use MCP Inspector to connect to local or remote servers, inspect capabilities, call tools, read resources, test prompts, and diagnose failures before release.

Build an MCP server in TypeScript with focused tools, validated schemas, local and remote transports, Inspector tests, and production security controls.

An MCP server exposes tools, resources, or prompts through a standard protocol so an AI application can discover and use external capabilities.

Triage open Blumira findings by severity, presenting a prioritized list for review

Deep investigation of a specific Blumira finding with details, context, and comment history

MSP dashboard showing all managed accounts with open finding counts and severity breakdown

Resolve a Blumira finding with the appropriate resolution type and notes

Overall security posture review including open findings by severity, agent coverage, and trends

Run the complete CIPP M365 offboarding workflow for a departing user — capture audit state, revoke access, handle mailbox, reclaim licenses

Generate a portfolio-wide M365 security posture report — Secure Score equivalents, MFA enrollment, conditional access coverage, and domain authentication across all managed tenants

Find tenants that have drifted from the MSP's configured CIPP standards baseline — missing standards, standards in Report-only mode, recent compliance failures

Quick health snapshot for a single tenant — BPA failures, conditional access enforcement, MFA gaps, domain authentication, standards compliance

Log a time entry (billable activity) against a Clio matter

Consolidated view of one Clio matter — contacts, open tasks, recent activities, recent communications, and bills

Search Clio contacts by name, company, or email

Search or list Clio matters by name/client and status

Capacity forecast for cloud resources, scoped to a resource type or covering everything connected

Cloud cost anomaly and reclaimable-spend report for a given window

Full network health sweep across all connected network-monitoring tools — devices down, degraded links, and topology changes

Report control and configuration drift since the last known-good baseline for a client or the whole portfolio

Build a source-cited compliance evidence package for a client against a named framework

Draft evidence-backed answers to the standard cyber-insurance questionnaire for a client

List computers in ConnectWise Automate with optional filters

AI coding platform for teams

AI Multi-Agent Framework in .NET

Production-ready code examples for Telnyx AI Communications Infrastructure — Voice AI, SMS, SIP, and IoT APIs

UltraGameStudio - AI coding agent for game development: engine workflows, gameplay code, and asset generation.

🦞 ResearchClawBench: Evaluating AI Agents for Automated Research from Re-Discovery to New-Discovery

The context-aware model router that learns & adapts to your long-horizon coding agent workflows. Lightweight & extensible, works with any harnesses, any models,…

Open-source sandboxes where coding agents build and deploy. Spin up isolated environments where Claude Code, Cursor, and other agents code and deploy software.

Native desktop UI for Claude Code with orchestration, streaming, background agents, and multi-provider support. Built with Tauri + React.

OpenCode mobile client via Telegram: run and monitor AI coding tasks from your phone while everything runs locally on your machine. Scheduled tasks support.

Terminal session manager for AI coding agents. One TUI for Claude, Gemini, OpenCode, Codex, and more.

Exposes internet search tools for use by LLM-backed Assist in Home Assistant

Templates and workflow for generating PRDs, Tech Designs, and MVP and more using LLMs for AI IDEs

Versus Incident is the self-hosted AI SRE agent. It learns what your system normally look like and escalates only what is new or unexpected issues — routing to…

Browser-native side panel for Hermes Agent — connect web context to your local Hermes runtime.

Agentic-friendly CLI generator for APIs: turn Swagger, OpenAPI, and google.api.http protos into single-binary CLIs with catalogs and generated Skills.

Open-source agent platform for Global × China enterprises — wire every system through one agent core. Self-hosted, any LLM.

Official python implementation of UTCP. UTCP is an open standard that lets AI agents call any API directly, without extra middleware.

An agent small enough to run anywhere. A minimal agentic runtime in C — ~380 lines, 54KB binary, ~2MB RAM. A skill file + an LLM + a shell loop, no framework.

AgentiLoop Agent! An Autonomous Agentic Agent for Mac, and exclusive Apple only harnesss. Suppprtd automation, scripting, coding, build anything and more. Power…

微信公众号 AI 运营助手 | 选题、写稿、审稿、排版、配图、发布全流程 Skill，支持 OpenClaw / Claude Code / Cursor / Codex