LLM Mart Basic

Apply the scGPT single-cell foundation model (Cui 2024) to annotate and embed cells — zero-shot and fine-tuned cell-type annotation, gene/cell embeddings, batch integration, and gene-regulatory / perturbation inference from AnnData. Use when annotating cell types with a pretraine

Run RNA velocity analysis with scVelo on single-cell RNA-seq data — estimate cell-state transitions from spliced/unspliced mRNA dynamics, infer trajectory direction, compute latent time, and identify driver genes. Use when adding directionality to trajectories or studying differe

Train deep generative models for single-cell omics with scvi-tools — probabilistic batch correction and integration (scVI), reference-mapping transfer learning (scArches), differential expression with uncertainty, and multimodal models (totalVI for CITE-seq, MultiVI for multiome)

Analyzes spatial transcriptomics with squidpy (1.8.x) on AnnData and SpatialData objects, routing platforms correctly: Visium spots use spatial_neighbors(coord_type='grid') and pair with deconvolution, while Xenium/MERFISH single-cell data use coord_type='generic'/Delaunay neighb

Store and query genomic variant data at scale with TileDB-VCF — ingest VCF/BCF into compressed TileDB arrays, add samples incrementally, run fast parallel region/sample queries, and export back to VCF. Use when managing population-genomics variant datasets that are too large for

Wraps RDKit in a high-level, pandas-friendly datamol interface with sensible defaults for everyday drug discovery — SMILES/SDF loading into DataFrames, molecule standardization, descriptors, fingerprints, Butina clustering, 3D conformer generation, scaffold analysis, and parallel

Runs molecular machine learning with DeepChem — diverse featurizers, pre-built MoleculeNet benchmark datasets, and pre-trained models (ChemBERTa, GROVER) for property prediction (ADMET, toxicity, solubility) via traditional ML or graph neural networks. Use when running end-to-end

Predicts protein-ligand binding poses with DiffDock diffusion-based molecular docking from PDB structures and SMILES, producing pose confidence scores for virtual screening and structure-based drug design. Use when docking ligands into a protein, generating binding poses, or scre

Computes mass-spectral similarity and identifies compounds for metabolomics with matchms — comparing mass spectra, scoring similarity (cosine, modified cosine), and searching spectral libraries to annotate unknowns. Use when matching MS/MS spectra, identifying metabolites, or lib

Applies medicinal-chemistry filters with the medchem library — drug-likeness rules (Lipinski, Veber), PAINS filters, structural alerts, and molecular complexity metrics for compound prioritization and library cleanup. Use when filtering or triaging a compound library, flagging PA

Featurizes molecules for machine learning with molfeat — ECFP/MACCS/MAP4 fingerprints, RDKit and Mordred physicochemical descriptors, pharmacophore and shape descriptors, and pretrained embeddings (ChemBERTa, ChemGPT, CheMeleon) exposed as scikit-learn transformers that convert S

Queries the Precision Medicine Knowledge Graph (PrimeKG) for multiscale biomedical relationships across genes, drugs, diseases, phenotypes, pathways, and biological processes. Use when exploring drug-disease or gene-disease links, building disease-centric knowledge subgraphs, or

Loads Therapeutics Data Commons (TDC, PyTDC) AI-ready drug-discovery datasets and benchmarks — ADME, toxicity, drug-target interaction (DTI), scaffold splits, and molecular oracles for therapeutic ML and pharmacological prediction. Use when fetching a standardized benchmark datas

Provides the RDKit cheminformatics toolkit for low-level, fine-grained molecular primitives — SMILES/SDF parsing, descriptors (MW, LogP, TPSA), fingerprints, substructure/SMARTS search, 2D/3D coordinate generation, similarity, and reaction handling. Use when custom sanitization,

Drives the Rowan cloud quantum-chemistry platform via its Python API for computational chemistry — pKa prediction, geometry optimization, conformer searching, molecular property calculations, protein-ligand docking (AutoDock Vina), and AI protein cofolding (Chai-1, Boltz-1/2), wi

Builds PyTorch-native graph neural networks with TorchDrug for molecules and proteins, exposing custom GNN architectures, task/dataset abstractions, molecular generation, retrosynthesis planning, and knowledge-graph reasoning. Use when a project specifically needs TorchDrug's dat

Generates professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings — biomarker-stratified patient cohort analyses with outcomes and evidence-based treatment recommendation reports with decision algorithms, supporting GRADE evidence

Prepares ISO 13485 certification documentation for medical device Quality Management Systems (QMS) — gap analysis of existing documentation, Quality Manuals, required procedures and work instructions, and Medical Device Files. Use for ISO 13485 QMS documentation, conducting a doc

Processes and analyzes physiological biosignals with the NeuroKit2 Python toolkit — ECG, EEG, EDA, RSP, PPG, EMG, and EOG signals. Use when processing cardiovascular signals, brain activity, electrodermal responses, respiratory patterns, muscle activity, or eye movements, or when

Reads, writes, and manipulates DICOM (Digital Imaging and Communications in Medicine) medical imaging files with the pydicom Python library. Use when reading/writing/modifying DICOM data, extracting pixel data from CT, MRI, X-ray, or ultrasound images, anonymizing DICOM files, wo

Discovery worked. Ping worked. Every TCP connection timed out, and later the tunnel only worked when someone had a terminal open.

Every VM came back. The cluster did not. Declarative systems converge on config, and the datapath isn't config.

A surprising share of AI-in-the-terminal failures aren't the AI. They're zsh, and a version of bash from 2006.

A Claude Code plugin turns standalone project configuration into a namespaced, installable extension that teams and communities can update as one unit.

None of the safety came from the model. It came from six boring habits.

Skills package instructions and references. Subagents run work in a separate context and return results. They solve different problems and can be composed deliberately.

Six hours in, one step left, everything green, and the incident that didn't happen

CLAUDE.md carries persistent project context. Skills load reusable procedures when relevant. Separating stable facts from task-specific workflows keeps both easier to maintain.

Twenty minutes recovering secrets that never existed, and the one sentence from a human that ended it

An API request routing a model's tool call through an approval gate to a remote MCP server

31 config keys, two audits, and why the first one was wrong in both directions

The official MCP Registry stores standardized server metadata rather than package code. Publishers verify a namespace, describe installation or remote access, and submit immutable versions.

Everyone looks at the Dockerfile. The file that actually leaked the key was the project file.

Remote MCP authorization uses established OAuth standards, but secure integration still requires issuer validation, least-privilege scopes, protected token handling, and server-side enforcement.

"Copy it over and switch the reference" is two steps, and the outage lives in the one nobody checks

stdio fits local processes and prototypes. Streamable HTTP fits hosted services and shared integrations. The right choice follows where the capability runs and who must reach it.

The most important rule wasn't about what I could change. It was about what I was allowed to display.

Tools perform operations, resources expose readable context, and prompts provide reusable templates. Choosing the correct primitive makes an MCP server easier to understand and govern.

Use MCP Inspector to connect to local or remote servers, inspect capabilities, call tools, read resources, test prompts, and diagnose failures before release.

Build an MCP server in TypeScript with focused tools, validated schemas, local and remote transports, Inspector tests, and production security controls.

Summarize a single Freshdesk ticket and its full conversation thread — the request, what has happened, current SLA state, and the recommended next action

Add an action (note, update, or response) to an existing HaloPSA ticket

Check contract status, service entitlements, and billing information for a client

Create a new service ticket in HaloPSA

Search the HaloPSA knowledge base for articles and solutions

Search for configuration items/assets by name, serial number, type, or client

Search for HaloPSA clients by name, domain, or other attributes

Search for tickets in HaloPSA by various criteria

Display comprehensive ticket information including history, actions, and related entities

View SLA status across tickets, including approaching breaches and at-risk tickets

Update fields on an existing HaloPSA ticket including status, priority, and assignment

Create a new deal in HubSpot with company association

Log a note or create a task on a HubSpot contact, company, or deal

Find a HubSpot company by name or domain and show associated contacts and deals

Summarize the HubSpot deal pipeline - deals per stage, total value, and expected close dates

Search HubSpot contacts by name, email, or company

Search HubSpot deals by name, stage, or company

Find a company in Hudu by name

Retrieve a password from Hudu (with security logging)

Find an asset in Hudu by name, hostname, serial number, or IP address

AI assistant in Telegram that remembers everything and helps you run your life. Self-hosted in one command.

知更 — 本地 AI 的上下文与记忆层。Mac 上用语音输入、情境代回并调度 Codex / Claude Code；iOS 正在成为随身记忆终端和本地 Agent 遥控器。Local-first · BYOK.

Agent skill that turns Claude Code / Codex into a motion-design studio for voiceover-driven explainer videos — word-level voiceover sync, 78 motion recipe cards…

CoCo Super Intelligence is the orchestration layer that turns Claude Code, Cursor, or Codex into an engineering department: a routed advisory board, 185 skills,…

Deploy AI agent teams at scale without compromise

大师.skill — 输入行业，自动调研 6 轨[行业大佬 / 工具地图 / 工作流 / 知识正典 / 信息源 / 术语标准] → 提炼为可运行的行业 Master OS skill；装到任意 Claude Code / OpenClaw / Codex / Hermes agent 即让其进入「这一行的资深人」模式。…

Notion MCP server for Claude, Cursor, ChatGPT & Claude Desktop. Connect AI agents to Notion via Model Context Protocol — pages, databases, blocks, comments, fil…

Hook-based token compressor for 5 AI CLI hosts (Claude Code, Copilot CLI, OpenCode, Gemini CLI, Codex CLI). Up to 95% bash compression, signature-mode for code…

Model-neutral agent desktop/runtime for private, enterprise, and OpenAI-compatible / Anthropic-compatible model API. Tested on DeepSeek, Qwen, Kimi, GLM models.…

AI agent skill for end-to-end hotel search and booking—compare live rates across leading OTAs and hotel suppliers, verify availability, book stays, and manage r…

More than just Karpathy’s LLM Wiki, 100% local with Ollama. Drop Markdown notes → AI extracts concepts → your Obsidian wiki auto-links and grows. Zero sharing.…

Claude Code Guide - Setup, Commands, workflows, agents, skills & tips-n-tricks from beginner to power user!

A magical tool that changes how you use Agents. Install once — every Agent automatically discovers and uses all your MCP tools, and saves your tokens along the…

Open-source 24/7 Cowork app for OpenClaw, Hermes, Claude Code, Codex, OpenCode and 20+ more CLI Agent | Customize your assistants | Team them up｜Star if you lik…

AgenticX is a unified, production-ready multi-agent platform — Python SDK + CLI (agx) + Studio server + Machi desktop app. Features Meta-Agent orchestration, 15…

Query, provision and operate Cloud, SaaS, API and Model Context Protocol (MCP) resources through a unified SQL-based framework for humans and AI agents.

Open-source AI job search: scan job portals, evaluate listings into a structured A-H report with a global 1-5 score, tailor your CV, track applications — runs l…

A self-healing scraper for hostile sites: broken selectors repair themselves, browser rendering kicks in when needed, and a coherent identity layer (Chrome TLS…

Lightweight AI-native workflow builder for individuals and small teams — describe your idea in natural language, get a runnable workflow on a visual canvas, pub…

Minimal AI coding agent (~1,000 lines of Python) inspired by Claude Code. Works with any LLM. Think NanoGPT for coding agents. Formerly NanoCoder.