LLM Mart Basic

Predict protein 3D structures with AlphaFold2 via ColabFold — MMseqs2-accelerated MSAs, monomer and AlphaFold2-Multimer complex folding, and confidence-based validation (pLDDT, pTM/ipTM, PAE). Use when folding a protein sequence or complex from FASTA, generating a predicted struc

Build, slice, concatenate, read, and write AnnData annotated data matrices (obs, var, X, layers, obsm, uns) — the scverse data STRUCTURE, not an analysis pipeline. Use when creating or wrangling .h5ad/zarr files, managing cell and gene annotations, concatenating batches, or handl

Infer gene regulatory networks (GRNs) from expression matrices using arboreto's scalable GRNBoost2 and GENIE3 tree-ensemble algorithms with Dask-distributed computation. Use when analyzing bulk or single-cell RNA-seq transcriptomics to map transcription-factor-to-target-gene regu

Manipulate biological sequences, parse FASTA/GenBank/PDB files, run phylogenetics, and access NCBI/PubMed programmatically via Biopython (Bio.SeqIO, Bio.Entrez, Bio.PDB, Bio.Blast). Use when scripting custom bioinformatics pipelines, batch-processing sequence files, automating BL

Query 40+ bioinformatics web services through one consistent Python API with bioservices (UniProt, KEGG, ChEMBL, Reactome, Ensembl, NCBI and more). Use when a workflow must hit multiple databases together, map identifiers across services, or run cross-database analyses — for quic

Runs NCBI BLAST+ 2.17.0 sequence searches from the command line: makeblastdb (with -parse_seqids), blastn/blastp/blastx/tblastn with tabular -outfmt 6/7 for parsing, correct -task choice (megablast vs blastn vs blastn-short), -taxids/-negative_taxids taxonomic scoping, and -mt_mo

Co-fold biomolecular complexes with Boltz-2, an open AlphaFold3-style model — predict protein + ligand (SMILES/CCD), protein + nucleic-acid, and multi-chain structures in one pass, with binding-affinity prediction. Use when folding a protein together with a small-molecule ligand,

Predict genome-wide functional genomics tracks from DNA sequence with Borzoi (Linder 2025) — a sequence-to-function model outputting RNA-seq, CAGE, ATAC, and ChIP coverage across long context, used to score non-coding and regulatory variant effects. Use when predicting functional

Query the CZ CELLxGENE Census (200M+ cells) programmatically via cellxgene-census and TileDB-SOMA, slicing expression by tissue, disease, or cell type and returning AnnData. Use when pulling reference single-cell RNA-seq data from the largest curated public atlas, running populat

Predict biomolecular complexes with Chai-1, an open AlphaFold3-style model that folds multi-entity assemblies (proteins, ligands, nucleic acids) from a single typed FASTA — strong on antibody–antigen and protein–ligand complexes, with optional MSA and restraint inputs. Use when p

Build and analyze genome-scale constraint-based metabolic models with COBRApy — flux balance analysis (FBA), flux variability analysis (FVA), gene and reaction knockouts, flux sampling, and SBML model I/O. Use when simulating metabolic networks, predicting growth or knockout phen

Process and visualize deep-sequencing coverage with the deepTools CLI — convert BAM to bigWig (bamCoverage), build log2 ratio tracks (bamCompare), run QC (multiBamSummary correlation, PCA, plotFingerprint), apply the ATAC-seq Tn5 shift (alignmentSieve --ATACshift), and make TSS/p

Run ESM protein language models — ESMC for embeddings and representations, ESMFold2 for structure prediction, and ESM3 for generative multimodal protein design across sequence, structure, and function — locally or through the hosted Biohub Platform API (formerly Forge). Use when

Manipulate, annotate, and render phylogenetic trees programmatically with the ETE Toolkit (ete3) — parse and edit Newick/NHX, detect duplication/speciation events, infer orthology and paralogy, query NCBI taxonomy, and export PDF/SVG figures. Use when traversing or reformatting t

Parse and write FCS (Flow Cytometry Standard) files v2.0-3.1 with FlowIO — extract event data as NumPy arrays, read $-keyword metadata and channel/parameter definitions, and convert events to CSV or pandas DataFrame. Use when loading raw .fcs flow-cytometry files, inspecting chan

Run fast one-liner queries to 20+ bioinformatics databases from the gget CLI or Python — gene info (Ensembl), BLAST, AlphaFold structures, Enrichr enrichment, and more. Use for quick interactive lookups of genes, sequences, structures, or pathways — for batch processing or advanc

Analyze and engineer protein glycosylation — scan sequences for N-glycosylation sequons (N-X-S/T), predict O-glycosylation hotspots, and reach curated glycoengineering tools (NetOGlyc, GlycoShield, GlycoWorkbench). Use when identifying or designing glycosylation sites, optimizing

Extract and preprocess tiles from whole-slide images (WSI) with histolab — OpenSlide-backed slide loading, tissue detection and masks, Random/Grid/Score tile extraction, and image/morphological filters for H&E preprocessing. Use when the user needs lightweight WSI slide preproces

Manage, annotate, and trace biological data with LaminDB, an open-source FAIR data framework that makes datasets queryable, versioned, and reproducible. Use when registering or querying biological datasets (scRNA-seq, spatial, flow cytometry), validating and curating data against

Design protein sequences around bound ligands, metals, and nucleic acids with LigandMPNN (Dauparas 2023) — inverse folding that conditions on non-protein context, so binding-pocket and metal-site residues are chosen to fit the actual ligand. Use when designing a small-molecule or

Every VM came back. The cluster did not. Declarative systems converge on config, and the datapath isn't config.

A surprising share of AI-in-the-terminal failures aren't the AI. They're zsh, and a version of bash from 2006.

A Claude Code plugin turns standalone project configuration into a namespaced, installable extension that teams and communities can update as one unit.

None of the safety came from the model. It came from six boring habits.

Skills package instructions and references. Subagents run work in a separate context and return results. They solve different problems and can be composed deliberately.

Six hours in, one step left, everything green, and the incident that didn't happen

CLAUDE.md carries persistent project context. Skills load reusable procedures when relevant. Separating stable facts from task-specific workflows keeps both easier to maintain.

Twenty minutes recovering secrets that never existed, and the one sentence from a human that ended it

An API request routing a model's tool call through an approval gate to a remote MCP server

31 config keys, two audits, and why the first one was wrong in both directions

The official MCP Registry stores standardized server metadata rather than package code. Publishers verify a namespace, describe installation or remote access, and submit immutable versions.

Everyone looks at the Dockerfile. The file that actually leaked the key was the project file.

Remote MCP authorization uses established OAuth standards, but secure integration still requires issuer validation, least-privilege scopes, protected token handling, and server-side enforcement.

"Copy it over and switch the reference" is two steps, and the outage lives in the one nobody checks

stdio fits local processes and prototypes. Streamable HTTP fits hosted services and shared integrations. The right choice follows where the capability runs and who must reach it.

The most important rule wasn't about what I could change. It was about what I was allowed to display.

Tools perform operations, resources expose readable context, and prompts provide reusable templates. Choosing the correct primitive makes an MCP server easier to understand and govern.

Use MCP Inspector to connect to local or remote servers, inspect capabilities, call tools, read resources, test prompts, and diagnose failures before release.

Build an MCP server in TypeScript with focused tools, validated schemas, local and remote transports, Inspector tests, and production security controls.

An MCP server exposes tools, resources, or prompts through a standard protocol so an AI application can discover and use external capabilities.

List upcoming contract and subscription renewals within a window, sorted by date

Run the license true-up reconciliation for one client or the whole portfolio

Search Freshdesk tickets with the Freshdesk query language — filter by status, priority, agent, group, type, tag, and date — and return a ranked, readable result list

Summarize a single Freshdesk ticket and its full conversation thread — the request, what has happened, current SLA state, and the recommended next action

Add an action (note, update, or response) to an existing HaloPSA ticket

Check contract status, service entitlements, and billing information for a client

Create a new service ticket in HaloPSA

Search the HaloPSA knowledge base for articles and solutions

Search for configuration items/assets by name, serial number, type, or client

Search for HaloPSA clients by name, domain, or other attributes

Search for tickets in HaloPSA by various criteria

Display comprehensive ticket information including history, actions, and related entities

View SLA status across tickets, including approaching breaches and at-risk tickets

Update fields on an existing HaloPSA ticket including status, priority, and assignment

Create a new deal in HubSpot with company association

Log a note or create a task on a HubSpot contact, company, or deal

Find a HubSpot company by name or domain and show associated contacts and deals

Summarize the HubSpot deal pipeline - deals per stage, total value, and expected close dates

Search HubSpot contacts by name, email, or company

Search HubSpot deals by name, stage, or company

AI skill for OpenClaw & Claude Code — recommend from 10000+ Nano Banana Pro (Gemini) image prompts. Smart search by use case, content remix, sample images.

嘉立创EDA专业版(EasyEDA Pro)自动化：给 AI harness 装上画板的「手」—— 一套 typed 原理图/PCB 动作，CLI / Agent Skill / stdio MCP 三形态融合接入。承接嘉立创「不以卖板赚钱，以培养中国工程师为己任」 | EasyEDA Pro automation:…

Claude Code session log viewer for JSONL files in ~/.claude/projects. Browse conversations, tool calls, tokens, and live tail sessions on desktop, web, and TUI.

Shared memory MCP server — persistent, searchable, cross-client Claude, Opencode

OpenAI Codex CLI session log viewer for JSONL files in ~/.codex/sessions. Browse conversations, tool calls, tokens, collaboration chains, and live sessions on d…

High-performance Google Drive CLI and Model Context Protocol (MCP) Server for LLM/AI agents. Natively execute Google Apps Script (GAS) under a secure whiteliste…

"Vibe-Trading: Your Personal Trading Agent"

Local-first chat history analyzer with AI. | 本地优先的 AI 聊天记录分析工具

Official Oxylabs MCP integration

Persistent memory for Claude Code & Codex CLI. Auto-extracted knowledge graph, multi-representation embeddings, 3D WebGL visualization. LongMemEval R@5=97.45%.…

One person, a team of agents. Multi-session CLI that collaborates across terminals; /goal keeps long tasks running; WeChat/WeCom/Feishu gateway lets you call th…

AI 基础知识 - GPU 架构、CUDA 编程、大模型基础及AI Agent 相关知识。

Self-hosted, open-source agent skill registry for enterprises. Publish & version skill packages, govern with RBAC and audit logs, deploy on-premise with Docke…

深度调研报告生成 Skill — 一条命令，十分钟出券商级深度调研报告 / Professional deep research report generation Skill · Supports 19 languages

The OKF toolkit for Claude Code — author, maintain, validate & visualize Open Knowledge Format bundles. Plugin, agent skills, and a GitHub Action.

Autonomous AI pentesting agents — real-time reconnaissance, vulnerability detection, and exploitation orchestration. Go + TypeScript.

Native macOS and iOS App for the Hermes AI agent — multi-window, multi-server (local + remote over SSH). Chat, dashboard, sessions, memory, cron, MCP, and more.

Multiplayer Claude Code and Codex. Self-hosted team workspace for Claude Code and Codex. Multi-user, browser-based, AI mates with memory.

Every past session, subagent, and workflow -- queryable by your agent, browsable by you

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