LLM Mart Basic

Run RNA velocity analysis with scVelo on single-cell RNA-seq data — estimate cell-state transitions from spliced/unspliced mRNA dynamics, infer trajectory direction, compute latent time, and identify driver genes. Use when adding directionality to trajectories or studying differe

Train deep generative models for single-cell omics with scvi-tools — probabilistic batch correction and integration (scVI), reference-mapping transfer learning (scArches), differential expression with uncertainty, and multimodal models (totalVI for CITE-seq, MultiVI for multiome)

Analyzes spatial transcriptomics with squidpy (1.8.x) on AnnData and SpatialData objects, routing platforms correctly: Visium spots use spatial_neighbors(coord_type='grid') and pair with deconvolution, while Xenium/MERFISH single-cell data use coord_type='generic'/Delaunay neighb

Store and query genomic variant data at scale with TileDB-VCF — ingest VCF/BCF into compressed TileDB arrays, add samples incrementally, run fast parallel region/sample queries, and export back to VCF. Use when managing population-genomics variant datasets that are too large for

Wraps RDKit in a high-level, pandas-friendly datamol interface with sensible defaults for everyday drug discovery — SMILES/SDF loading into DataFrames, molecule standardization, descriptors, fingerprints, Butina clustering, 3D conformer generation, scaffold analysis, and parallel

Runs molecular machine learning with DeepChem — diverse featurizers, pre-built MoleculeNet benchmark datasets, and pre-trained models (ChemBERTa, GROVER) for property prediction (ADMET, toxicity, solubility) via traditional ML or graph neural networks. Use when running end-to-end

Predicts protein-ligand binding poses with DiffDock diffusion-based molecular docking from PDB structures and SMILES, producing pose confidence scores for virtual screening and structure-based drug design. Use when docking ligands into a protein, generating binding poses, or scre

Computes mass-spectral similarity and identifies compounds for metabolomics with matchms — comparing mass spectra, scoring similarity (cosine, modified cosine), and searching spectral libraries to annotate unknowns. Use when matching MS/MS spectra, identifying metabolites, or lib

Applies medicinal-chemistry filters with the medchem library — drug-likeness rules (Lipinski, Veber), PAINS filters, structural alerts, and molecular complexity metrics for compound prioritization and library cleanup. Use when filtering or triaging a compound library, flagging PA

Featurizes molecules for machine learning with molfeat — ECFP/MACCS/MAP4 fingerprints, RDKit and Mordred physicochemical descriptors, pharmacophore and shape descriptors, and pretrained embeddings (ChemBERTa, ChemGPT, CheMeleon) exposed as scikit-learn transformers that convert S

Queries the Precision Medicine Knowledge Graph (PrimeKG) for multiscale biomedical relationships across genes, drugs, diseases, phenotypes, pathways, and biological processes. Use when exploring drug-disease or gene-disease links, building disease-centric knowledge subgraphs, or

Loads Therapeutics Data Commons (TDC, PyTDC) AI-ready drug-discovery datasets and benchmarks — ADME, toxicity, drug-target interaction (DTI), scaffold splits, and molecular oracles for therapeutic ML and pharmacological prediction. Use when fetching a standardized benchmark datas

Provides the RDKit cheminformatics toolkit for low-level, fine-grained molecular primitives — SMILES/SDF parsing, descriptors (MW, LogP, TPSA), fingerprints, substructure/SMARTS search, 2D/3D coordinate generation, similarity, and reaction handling. Use when custom sanitization,

Drives the Rowan cloud quantum-chemistry platform via its Python API for computational chemistry — pKa prediction, geometry optimization, conformer searching, molecular property calculations, protein-ligand docking (AutoDock Vina), and AI protein cofolding (Chai-1, Boltz-1/2), wi

Builds PyTorch-native graph neural networks with TorchDrug for molecules and proteins, exposing custom GNN architectures, task/dataset abstractions, molecular generation, retrosynthesis planning, and knowledge-graph reasoning. Use when a project specifically needs TorchDrug's dat

Generates professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings — biomarker-stratified patient cohort analyses with outcomes and evidence-based treatment recommendation reports with decision algorithms, supporting GRADE evidence

Prepares ISO 13485 certification documentation for medical device Quality Management Systems (QMS) — gap analysis of existing documentation, Quality Manuals, required procedures and work instructions, and Medical Device Files. Use for ISO 13485 QMS documentation, conducting a doc

Processes and analyzes physiological biosignals with the NeuroKit2 Python toolkit — ECG, EEG, EDA, RSP, PPG, EMG, and EOG signals. Use when processing cardiovascular signals, brain activity, electrodermal responses, respiratory patterns, muscle activity, or eye movements, or when

Reads, writes, and manipulates DICOM (Digital Imaging and Communications in Medicine) medical imaging files with the pydicom Python library. Use when reading/writing/modifying DICOM data, extracting pixel data from CT, MRI, X-ray, or ultrasound images, anonymizing DICOM files, wo

Develops, tests, and validates clinical machine learning models with the PyHealth 2.x healthcare AI toolkit. Use when working with electronic health records (EHR), clinical prediction tasks (mortality, readmission, length of stay, drug recommendation), medical coding systems (ICD

Discovery worked. Ping worked. Every TCP connection timed out, and later the tunnel only worked when someone had a terminal open.

Every VM came back. The cluster did not. Declarative systems converge on config, and the datapath isn't config.

A surprising share of AI-in-the-terminal failures aren't the AI. They're zsh, and a version of bash from 2006.

A Claude Code plugin turns standalone project configuration into a namespaced, installable extension that teams and communities can update as one unit.

None of the safety came from the model. It came from six boring habits.

Skills package instructions and references. Subagents run work in a separate context and return results. They solve different problems and can be composed deliberately.

Six hours in, one step left, everything green, and the incident that didn't happen

CLAUDE.md carries persistent project context. Skills load reusable procedures when relevant. Separating stable facts from task-specific workflows keeps both easier to maintain.

Twenty minutes recovering secrets that never existed, and the one sentence from a human that ended it

An API request routing a model's tool call through an approval gate to a remote MCP server

31 config keys, two audits, and why the first one was wrong in both directions

The official MCP Registry stores standardized server metadata rather than package code. Publishers verify a namespace, describe installation or remote access, and submit immutable versions.

Everyone looks at the Dockerfile. The file that actually leaked the key was the project file.

Remote MCP authorization uses established OAuth standards, but secure integration still requires issuer validation, least-privilege scopes, protected token handling, and server-side enforcement.

"Copy it over and switch the reference" is two steps, and the outage lives in the one nobody checks

stdio fits local processes and prototypes. Streamable HTTP fits hosted services and shared integrations. The right choice follows where the capability runs and who must reach it.

The most important rule wasn't about what I could change. It was about what I was allowed to display.

Tools perform operations, resources expose readable context, and prompts provide reusable templates. Choosing the correct primitive makes an MCP server easier to understand and govern.

Use MCP Inspector to connect to local or remote servers, inspect capabilities, call tools, read resources, test prompts, and diagnose failures before release.

Build an MCP server in TypeScript with focused tools, validated schemas, local and remote transports, Inspector tests, and production security controls.

Update implementation documentation including specs, status, and best practices

Use structured stepper approach for problem-solving and project development

Write unit and integration tests

Developer agent — implements features based on technical design, follows TDD patterns, and produces clean, tested code

Autonomous iteration loop — reads progress, selects role, executes, verifies, commits, and moves to next task without waiting

Pair programming mode — step-by-step collaboration with 5 confirmation checkpoints for learning and sensitive operations

Product Manager agent — analyzes requirements, creates REQ documents, and breaks down features into actionable items

Configure claude-hud as your Claude Code statusline

Grade this repo's CLAUDE.md / AGENTS.md (0–100) and return a worst-first fix list

Scaffold a CLAUDE.md for this repo from battle-tested templates, filled in with the project's real commands

Prompt optimizer — rewrite this request into an optimized prompt (ultrathink), then carry it out

Configure codex-hud statusline display options (guided interactive flow)

Show last 30 days Codex cost breakdown

Show today's Codex cost breakdown

Show last 7 days Codex cost breakdown

Configure or update the OpenAI Admin API key (enables /codex-hud:costs-*)

Install codex-hud statusline (automatic, idempotent)

Quick one-line summary of today's Codex activity (cost shown if Admin key configured)

Remove the codex-hud statusline integration (restores your previous statusline)

Показать состояние гейта качества 1С — какие файлы ждут проверки

Persistent session memory for AI coding agents — local-first, with on-device inference, associative recall, and drift detection. Works with Claude Code, Cursor,…

Run Hermes Agent and OpenClaw on the same WeChat account

An AI co-scientist running on your desktop. Claude Science but better.

Emotion Ball 是一套面向 AI 助手的表情引擎:32 种状态表情全部由纯 SVG 与原生 JavaScript 实时驱动,零框架、零图片资源。AI 侧只需输出一个 emotionId,小球即可切换到对应表情,可直接用作聊天机器人、桌面宠物、悬浮助手的情绪表达层。

Agent communication SDK. The open-source agent communication layer for AI agents — email, WhatsApp, Slack, Discord, Telegram, SMS. Python & TypeScript.

The micro-VM for AI agents — light enough to embed on your laptop, elastic enough to power an agentic cloud.

Give each AI agent its own isolated machine with root, Docker, and systemd. Active defense detects and stops threats automatically.

Webhook integration skills for AI coding agents (Claude Code, Cursor, Copilot). Step-by-step guidance for setting up webhook receivers, signature verification,…

Token burn reducer and focus keeper for Claude Code, Codex, Copilot, Gemini CLI, and more: surgical read hints, PDF/Office/CSV/markdown file interception, 160+…

RuvNet Brain — a downloadable, source-grounded brain for Claude Code over Reuven Cohen's (rUv's) RuvNet stack: RuVector/RVF, Ruflo, AgentDB, RuLake, SPARC + 21…

💼 One MCP server to search job boards and company career sites

C++ MCP SDK - build Model Context Protocol (MCP) servers and clients in C++ / CPP. Enterprise-grade security, observability, connectivity. Stdio, HTTP+SSE, Stre…

Open-Source AI Presentation Generator and API (Gamma, Canva, Beautiful AI, Decktopus, Presentations AI Alternative)

Secure, Fast, and Extensible Sandbox runtime for AI agents.

Give your AI agent eyes to see the entire internet. Read & search Twitter, Reddit, YouTube, GitHub, Bilibili, XiaoHongShu — one CLI, zero API fees.

Browser Harness | Self-healing harness that enables LLMs to complete any task.

The World's First Agentic IDE. Visual dashboard: live sessions, task management, code editor, terminal. Epic Swarm parallel workflows. Auto-proceed rules. Autom…

Agenta is a workspace where you and your team build agents and automations.

Terminal Director. One lightweight app, eight features, your whole dev workflow in a single window.

AI turns documents or topics into real, native PowerPoint decks—with native shapes, transitions and animations, data-backed charts and tables on demand, audio n…