LLM Mart Basic
@llm-mart · Joined Jun 2026
Run the standard single-cell RNA-seq analysis pipeline with Scanpy on AnnData — QC filtering, normalization, dimensionality reduction (PCA, UMAP, t-SNE), Leiden/Louvain clustering, marker/differential expression, PAGA trajectories, and plotting. Use when analyzing scRNA-seq data
Apply the scGPT single-cell foundation model (Cui 2024) to annotate and embed cells — zero-shot and fine-tuned cell-type annotation, gene/cell embeddings, batch integration, and gene-regulatory / perturbation inference from AnnData. Use when annotating cell types with a pretraine
Run RNA velocity analysis with scVelo on single-cell RNA-seq data — estimate cell-state transitions from spliced/unspliced mRNA dynamics, infer trajectory direction, compute latent time, and identify driver genes. Use when adding directionality to trajectories or studying differe
Train deep generative models for single-cell omics with scvi-tools — probabilistic batch correction and integration (scVI), reference-mapping transfer learning (scArches), differential expression with uncertainty, and multimodal models (totalVI for CITE-seq, MultiVI for multiome)
Analyzes spatial transcriptomics with squidpy (1.8.x) on AnnData and SpatialData objects, routing platforms correctly: Visium spots use spatial_neighbors(coord_type='grid') and pair with deconvolution, while Xenium/MERFISH single-cell data use coord_type='generic'/Delaunay neighb
Store and query genomic variant data at scale with TileDB-VCF — ingest VCF/BCF into compressed TileDB arrays, add samples incrementally, run fast parallel region/sample queries, and export back to VCF. Use when managing population-genomics variant datasets that are too large for
Wraps RDKit in a high-level, pandas-friendly datamol interface with sensible defaults for everyday drug discovery — SMILES/SDF loading into DataFrames, molecule standardization, descriptors, fingerprints, Butina clustering, 3D conformer generation, scaffold analysis, and parallel
Runs molecular machine learning with DeepChem — diverse featurizers, pre-built MoleculeNet benchmark datasets, and pre-trained models (ChemBERTa, GROVER) for property prediction (ADMET, toxicity, solubility) via traditional ML or graph neural networks. Use when running end-to-end
Predicts protein-ligand binding poses with DiffDock diffusion-based molecular docking from PDB structures and SMILES, producing pose confidence scores for virtual screening and structure-based drug design. Use when docking ligands into a protein, generating binding poses, or scre
Computes mass-spectral similarity and identifies compounds for metabolomics with matchms — comparing mass spectra, scoring similarity (cosine, modified cosine), and searching spectral libraries to annotate unknowns. Use when matching MS/MS spectra, identifying metabolites, or lib
Applies medicinal-chemistry filters with the medchem library — drug-likeness rules (Lipinski, Veber), PAINS filters, structural alerts, and molecular complexity metrics for compound prioritization and library cleanup. Use when filtering or triaging a compound library, flagging PA
Featurizes molecules for machine learning with molfeat — ECFP/MACCS/MAP4 fingerprints, RDKit and Mordred physicochemical descriptors, pharmacophore and shape descriptors, and pretrained embeddings (ChemBERTa, ChemGPT, CheMeleon) exposed as scikit-learn transformers that convert S
Queries the Precision Medicine Knowledge Graph (PrimeKG) for multiscale biomedical relationships across genes, drugs, diseases, phenotypes, pathways, and biological processes. Use when exploring drug-disease or gene-disease links, building disease-centric knowledge subgraphs, or
Loads Therapeutics Data Commons (TDC, PyTDC) AI-ready drug-discovery datasets and benchmarks — ADME, toxicity, drug-target interaction (DTI), scaffold splits, and molecular oracles for therapeutic ML and pharmacological prediction. Use when fetching a standardized benchmark datas
Provides the RDKit cheminformatics toolkit for low-level, fine-grained molecular primitives — SMILES/SDF parsing, descriptors (MW, LogP, TPSA), fingerprints, substructure/SMARTS search, 2D/3D coordinate generation, similarity, and reaction handling. Use when custom sanitization,
Drives the Rowan cloud quantum-chemistry platform via its Python API for computational chemistry — pKa prediction, geometry optimization, conformer searching, molecular property calculations, protein-ligand docking (AutoDock Vina), and AI protein cofolding (Chai-1, Boltz-1/2), wi
Builds PyTorch-native graph neural networks with TorchDrug for molecules and proteins, exposing custom GNN architectures, task/dataset abstractions, molecular generation, retrosynthesis planning, and knowledge-graph reasoning. Use when a project specifically needs TorchDrug's dat
Generates professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings — biomarker-stratified patient cohort analyses with outcomes and evidence-based treatment recommendation reports with decision algorithms, supporting GRADE evidence
Prepares ISO 13485 certification documentation for medical device Quality Management Systems (QMS) — gap analysis of existing documentation, Quality Manuals, required procedures and work instructions, and Medical Device Files. Use for ISO 13485 QMS documentation, conducting a doc
Processes and analyzes physiological biosignals with the NeuroKit2 Python toolkit — ECG, EEG, EDA, RSP, PPG, EMG, and EOG signals. Use when processing cardiovascular signals, brain activity, electrodermal responses, respiratory patterns, muscle activity, or eye movements, or when
/autopilot
autopilot
Run autonomous hunt loop on a target — scope check → recon → rank surface → hunt → validate → report with configurable checkpoints. Usage: /autopilot target.com [--paranoid|--normal|--yolo]
/chain
chain
Build an exploit chain — given bug A, finds B and C to combine for higher severity and payout. Knows common chain patterns: IDOR→ATO, SSRF→cloud metadata, XSS→ATO, open redirect→OAuth theft, S3→bundle→secret→OAuth. Usage: /chain
/hunt
hunt
Active vulnerability hunting. Two-track dispatcher — asks Red Team vs WAPT, hands off to hunt-dispatch skill and sibling commands. Usage: /hunt target.com | /hunt *.target.com | /hunt targets.txt [--vuln-class X] [--source-code P] [--chrome]
/intel
intel
On-demand intelligence fetch for a target — CVEs, disclosed reports, new features. Pulls NVD/GitHub-Advisory CVEs + bundled disclosed reports + hunt memory context. Usage: /intel target.com
/memory-gc
memory-gc
Inspect or rotate the autopilot ledger JSONL files (findings.jsonl, negatives.jsonl). Caps file size and keeps N rotated backups so memory does not grow unbounded.
/pickup
pickup
Pick up a previous hunt on a target — shows hunt history and untested surface from the autopilot ledger. Usage: /pickup target.com
/recon
recon
Run full recon pipeline on a target — subdomain enum (Chaos API + subfinder), live host discovery (dnsx + httpx), URL crawl (katana + waybackurls + gau), gf pattern classification, nuclei scan. Outputs to recon/<target>/ directory. Usage: /recon target.com
/remember
remember
Optional manual note on a target or the last confirmed finding. Capture is automatic during autopilot; this is for extra context. Usage: /remember
/report
report
Write a submission-ready bug bounty report. Generates H1/Bugcrowd/Intigriti/Immunefi format with CVSS 3.1 score, proof of concept, impact statement, and remediation. Run /validate first. Usage: /report
/scope
scope
Mandatory pre-flight scope check — verify an asset is in scope BEFORE any HTTP touch. Deterministic (deny-wins, default-deny) via engine/scope.py against the engagement's scope.md. Blocks out-of-scope testing. Usage: /scope <asset> [<asset> ...]
/surface
surface
Show ranked attack surface for a target from its recon manifest + hunt memory. Deterministic backing is `cbh surface <target>` (reads recon/<target>/manifest.json); LLM layer adds ledger signal. Usage: /surface target.com
/token-scan
token-scan
Meme coin and token security scan — checks for rug pull vectors (hidden mint, honeypot, fee manipulation, LP lock bypass, authority retention, bonding curve exploits, fake renounce, sandwich amplification). Manual 8-class grep audit (with an optional automated scanner if present). Usage: /token-scan <contract_path_or_dir> [--chain solana]
/triage
triage
Quick 7-Question Gate triage on a finding before writing a report. Kills N/A submissions before they happen. Faster than /validate — for quick go/no-go decisions. Usage: /triage
/validate
validate
Validate a finding — runs 7-Question Gate + 4-gate checklist. Kills weak findings before report writing. Prevents N/A submissions that hurt validity ratio. Usage: /validate
/web3-audit
web3-audit
Smart contract security audit — runs through 10 bug class checklist (accounting desync, access control, incomplete path, off-by-one, oracle errors, ERC4626, reentrancy, flash loan, signature replay, proxy/upgrade). Applies pre-dive kill signals first. Generates Foundry PoC template for confirmed findings. Usage: /web3-audit <contract.sol>
/README
README
Crabbox is a single CLI (`crabbox`). Commands are top-level, not nested under a
/actions
Actions
`crabbox actions` prepares a leased box from your repository's own GitHub
/adapter
Adapter
See [Runtime adapter stack](../features/runtime-adapter-stack.md) for the
/admin
Admin
`crabbox admin` groups trusted operator controls for coordinator-backed leases and the cloud resources behind them. Use it to inspect every lease the broker tracks, reconcile expired leases against live cloud state, force-release or delete a backing server, print provider IAM pol
/artifacts
Artifacts
`crabbox artifacts` turns a desktop lease into durable QA evidence: it collects
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