LLM Mart Basic

Execute ENCODE Whole Genome Bisulfite Sequencing (WGBS) pipeline from FASTQ to methylation calls. Child of pipeline-guide. Provides Nextflow execution with Docker and cloud deployment. Use when processing WGBS/bisulfite-seq data, calling methylation levels, generating bedMethyl f

Assess the scientific integrity and trustworthiness of publications before relying on their findings. Use this skill whenever evaluating a paper for a workflow, citing a study, building an analysis on published methods, or when a user asks about the reliability of a study. Checks

Evaluate ENCODE experiment quality using standard metrics and audit flags. Use when the user asks about data quality, wants to filter for high-quality experiments, needs to interpret quality metrics (FRiP, NSC, RSC, NRF, IDR, TSS enrichment, fragment size), wants to understand EN

Discover and characterize regulatory elements (enhancers, promoters, silencers, insulators, super-enhancers) using ENCODE data and the cCRE catalog. Use when the user wants to find candidate regulatory elements, identify active enhancers in a tissue, map promoter states, classify

Generate publication-ready methods sections, figure legends, supplementary tables, and data availability statements from ENCODE analysis provenance. Implements the scientific documentation standards requiring complete metadata reporting. Use when the user needs to write methods,

Conduct rigorous cross-study meta-analysis of scRNA-seq data from ENCODE, integrating multiple single-cell transcriptomic datasets for a tissue/cell type. Use when the user wants to answer "what cell types exist in my tissue and what genes define them?" by combining scRNA-seq dat

Search and explore ENCODE Project genomics data. Use when the user wants to find experiments, files, or explore what data is available for specific assays, organs, cell lines, or targets.

Set up the ENCODE Toolkit server connection. Use when the user needs help installing, configuring, or troubleshooting the ENCODE connector.

Find and work with ENCODE single-cell genomics data including scRNA-seq and scATAC-seq. Use when the user asks about single-cell experiments, cell type resolution, clustering from ENCODE data, deconvolution of bulk signals using single-cell references, or comparing single-cell vs

Track ENCODE experiments locally with publications, citations, and provenance. Use when the user wants to build a collection of experiments, manage citations, compare experiments, or track data provenance.

Query the UCSC Genome Browser REST API to retrieve regulatory tracks, DNA sequences, cCRE annotations, TF binding clusters, and track schemas for any genomic region. Use when the user wants to look up what regulatory elements exist at a genomic locus, retrieve DNA sequence under

Annotate genetic variants (GWAS hits, eQTLs, rare variants) with ENCODE functional data to interpret non-coding variation. Use when the user has variants of interest and wants to understand their regulatory context, identify causal variants from GWAS loci, assess variant impact o

Comprehensive guide for visualizing ENCODE data including deeptools heatmaps, IGV screenshots, UCSC track hubs, and publication-quality plots. Use when users need to create visualizations of ChIP-seq signal, peak landscapes, genome browser views, or any visual representation of E

Make software health, failure, degradation, and recovery visible through useful observability and diagnostics. Use when adding logs, metrics, traces, health checks, alerts, incident signals, or operational feedback.

Inspect the real repository, environment, dependencies, and runtime evidence before designing or changing software. Use for greenfield construction, unfamiliar codebases, uncertain behavior, or any task where assumptions could create rework.

Reflect on failures, incidents, reviews, and completed software work to turn evidence into durable tests, guardrails, documentation, and process improvements.

Debug software by making failures visible, reproducing them, finding contributing causes, and adding durable regression protection. Use for bugs, failing tests, incidents, regressions, flaky behavior, and unexplained production errors.

Improve software continuously through small, safe, behavior-preserving changes that reduce maintenance cost. Use for refactoring, cleanup, technical debt, naming, duplication, dead code, or post-change polish.

Choose simple, maintainable software designs by removing speculative complexity, comparing alternatives, and making explicit tradeoffs. Use for architecture, API, data-model, dependency, and scope decisions.

Implement software through small, repeatable, integrated vertical slices with clear exit criteria and honest verification. Use when a design is understood and code needs to be built or changed.

A green PR, a controller reporting success, and not one line of the new code running

Generate requirements from goal and research

Run or re-run research phase for current spec

Smart entry point that detects if you need a new spec or should resume existing

Show all specs and their current status

Switch active spec

Generate implementation tasks from design

Decompose a large feature into multiple dependency-aware specs (epic triage)

Check for or install a verified Tree Ring Memory CLI update without changing installation scope

This directory contains the command implementations for the fast-agent CLI.

They operate it without you.

Promised, measured, accepted. A number nobody signed is claimed, not delivered.

Prepare the meeting. One page from the record.

Find the receipt. A dated line, or it did not happen.

Diagnose trust. Process gap, or they stopped trusting you.

Generate, convert, and maintain animated GitHub-safe Markdown documents with animated SVG diagrams. Covers four SVG patterns (architecture flow, lifecycle loop, field carousel, timeline phases), guided interview for any doc type (README, architecture guide, runbook, API reference, tutorial, RFC, post-mortem, how-it-works, or custom), converting existing plain Markdown, diffing for stale diagrams, quality auditing, local preview, and multi-platform export. Use when asked to "create a README for X", "write an architecture doc", "animate this guide", "convert my doc to animated", "check if my diagrams are stale", or "export my doc for Confluence".

AWS profile management for MCP servers — discover profiles across SSO, Granted, and assumed-role chains, check credential TTL, switch profiles across VS Code and Claude Code MCP configs, and scan AWS Organization accounts.

Structured guidance for AWS CloudFront distributions, WAF web ACLs, Lambda@Edge, CloudFront Functions, Firewall Manager multi-account enforcement, and IAM/IRSA patterns. Covers OAC, cache policies, security headers, managed rule groups, rate limiting, FMS FIRST/MIDDLE/LAST ownership model, and production-ready Terraform generation.

Azure identity (Workload Identity, OIDC, Entra ID), resource tagging, AKS platform patterns, RBAC scoping, and production-readiness review — with Terraform generation.

Design, run, and debug Chaos Engineering experiments on Kubernetes using Litmus Chaos v3 and Chaos Mesh v2. Covers fault injection (pod-delete, network-loss, CPU stress, node-drain), steady-state hypothesis probes, GameDay runbooks, scheduled experiments, DORA feedback loop, and RBAC setup. Use when asked to "inject a pod fault", "run a GameDay", "schedule chaos experiments", or "debug why my ChaosEngine is stuck".

Bootstrap Checkov on a developer laptop, run static or plan-level Terraform security scanning for AWS/Azure/GCP/EKS, resolve private GitHub modules via gh CLI, generate pre-commit hooks, produce multi-format output (cli/json/sarif/junit), and fix violations with AI-generated patches. Use when asked to "scan my Terraform", "run checkov", "check my IaC for security issues", "set up checkov pre-commit", or "fix checkov findings".

Make any song you can imagine

Leading AI-powered video generation platform that specializes in creating hyper-realistic talking avatars

Hermes Agent is an open-source, self-improving autonomous AI agent developed by Nous Research

Kilo Code is a popular, open-source AI coding agent and "agentic engineering" platform designed to help developers build, refactor, and debug software faster

General-purpose agent in one static Go binary. ReAct loop, ACP server for IDEs, OpenAI-compatible REST API with embedded web UI, Telegram gateway, cron schedule…

Autonomous agent framework with structured memory, safety hooks, and loop management. Built by the agent that runs on it.

TSP自托管、零运维的 A 股「选股 + 监控 + 回测」量化工作台 | 基于 TickFlow 数据源 | LLM能力驱使策略定制+个股分析+复盘 | 自由接入第三方数据源与个性化扩展数据 | 个人开源 ,非TickFlow官方项目

Curated, verified Agent Skills powered by ModelStudio.

Run Claude Code, Codex, Antigravity, Cursor Agent and OpenCode as one runtime — persistent sessions, multi-agent councils, an OpenAI-compatible endpoint, an MCP…

pi had nothing (nothing), so I made something (something) — sorry mariozechner-senpai, I went ahead and lovingly soiled your pure pi for you. opinionated fork o…

A persistent workspace for development work that self-improves and continues beyond one session.

Open-source memory and context for user-aware agents: scoped memory, provenance, retrieval quality, correction, boundaries, evals, and MCP/HTTP access.

📚 A zero-dependency, git-backed micro-lesson library for AI Agents to asynchronously share and search verified debugging experience. Python stdlib only. | http…

Deterministic, local-first memory and guardrails for AI coding agents with no LLM in the hot path.

Deterministic spec-orchestration for local LLMs in the pi coding agent — drives prompts through refine→research→grill→compose→critique, with bundled web/docs/fe…

Native Safari browser automation for AI agents. 97 tools via AppleScript — zero overhead, keeps logins, runs silently in background. Drop-in alternative to Chro…

Agent OS: keep specialist agents in a hub, spin up a temporary orchestrator per task. Local-first, works with any model.

Git for agent memory. Branches, diffs, PRs, and rollback for what your agents know.

Multi-Provider AI Gateway - No personal logs by design. Model autodiscovery, Failover groups, High availability, Android companion app, and more - "Because we h…

Production-grade MCP server for MikroTik RouterOS with secure AI-native network automation.