LLM Mart Basic
@llm-mart · Joined Jun 2026
Conduct rigorous cross-study meta-analysis of scRNA-seq data from ENCODE, integrating multiple single-cell transcriptomic datasets for a tissue/cell type. Use when the user wants to answer "what cell types exist in my tissue and what genes define them?" by combining scRNA-seq dat
Search and explore ENCODE Project genomics data. Use when the user wants to find experiments, files, or explore what data is available for specific assays, organs, cell lines, or targets.
Set up the ENCODE Toolkit server connection. Use when the user needs help installing, configuring, or troubleshooting the ENCODE connector.
Find and work with ENCODE single-cell genomics data including scRNA-seq and scATAC-seq. Use when the user asks about single-cell experiments, cell type resolution, clustering from ENCODE data, deconvolution of bulk signals using single-cell references, or comparing single-cell vs
Track ENCODE experiments locally with publications, citations, and provenance. Use when the user wants to build a collection of experiments, manage citations, compare experiments, or track data provenance.
Query the UCSC Genome Browser REST API to retrieve regulatory tracks, DNA sequences, cCRE annotations, TF binding clusters, and track schemas for any genomic region. Use when the user wants to look up what regulatory elements exist at a genomic locus, retrieve DNA sequence under
Annotate genetic variants (GWAS hits, eQTLs, rare variants) with ENCODE functional data to interpret non-coding variation. Use when the user has variants of interest and wants to understand their regulatory context, identify causal variants from GWAS loci, assess variant impact o
Comprehensive guide for visualizing ENCODE data including deeptools heatmaps, IGV screenshots, UCSC track hubs, and publication-quality plots. Use when users need to create visualizations of ChIP-seq signal, peak landscapes, genome browser views, or any visual representation of E
Build comprehensive chromatin accessibility maps by aggregating ATAC-seq and DNase-seq narrowPeak data across multiple ENCODE experiments, donors, and labs. Use when the user wants to answer "where is chromatin accessible in my tissue?" by combining peak calls into a union peak s
Guide for multi-experiment batch operations: QC screening, batch download, comparison, and report generation across many ENCODE experiments simultaneously. Use when users need to process 5+ experiments together, create experiment comparison tables, perform batch quality checks, o
Install bioinformatics tools for ENCODE data analysis. Covers CLI tools (BWA, STAR, samtools, MACS2), R/Bioconductor packages (DESeq2, Seurat, ChIPseeker), Python packages (Scanpy, deeptools), and Nextflow pipeline infrastructure. Generates conda environments, R install scripts,
Guide for integrating CellxGene Census single-cell data with ENCODE bulk experiments. Use when users need cell-type-specific expression context for ENCODE regulatory data, want to deconvolve bulk ENCODE signals, or validate regulatory elements at single-cell resolution. Trigger o
Generate proper ENCODE citations for publications, grants, and presentations. Use when the user needs to cite ENCODE data, create bibliography entries, write acknowledgment sections, or ensure compliance with ENCODE data use policy.
Guide for annotating ENCODE regulatory variants with ClinVar clinical significance. Use when users need to check if variants in ENCODE peaks have clinical associations, find pathogenic variants in regulatory regions, or assess variant clinical impact. Trigger on: ClinVar, clinica
Compare ENCODE experiments across different biosamples, tissues, or cell lines to identify tissue-specific regulatory patterns. Use when the user wants cross-tissue comparison, cell-type comparison, tissue-specific elements, differential chromatin, biosample matching, disease vs
Cross-reference ENCODE data with PubMed, bioRxiv, ClinicalTrials.gov, Open Targets, GTEx, ClinVar, GWAS Catalog, gnomAD, Ensembl, and other scientific databases. Use when the user wants to find publications, preprints, or clinical trials related to ENCODE experiments, chain ENCOD
Use ENCODE functional genomics data for disease mechanism research. Use when the user wants to connect GWAS variants to regulatory elements, annotate disease-associated loci with functional data, identify therapeutic targets from epigenomic data, build disease regulatory models,
Download ENCODE genomics files (BED, FASTQ, BAM, bigWig, etc.) to the user's machine. Use when the user wants to download data files from ENCODE experiments.
Query the Ensembl REST API for regulatory feature annotations, variant effect prediction (VEP), coordinate liftover, gene lookups, and cross-references. Use when the user needs to annotate variants with VEP (consequence, CADD, REVEL, SpliceAI), check Ensembl Regulatory Build over
Build comprehensive epigenomic profiles for tissues or cell types using ENCODE data. Use when the user wants to characterize chromatin states, assemble histone modification panels, create epigenomic landscapes, run ChromHMM segmentation, identify super-enhancers or bivalent domai
/update
Update
Update the Hivemind plugin to the latest version
/disable
Disable
credo - Disable credo for this directory (silence onboarding and the [credo] line here, reversible)
/enable
Enable
credo - Enable credo for this directory (opt in; overrides a previous decline)
/explain
Explain
credo - Explain something in depth (what/why/example/consequences)
/migrate
Migrate
credo - Migrate an existing repo into the .credo/ structure
/project
Project
credo - Pin the target repo for credo's project layer (hub-aware), or show the resolved target
/psalm
Psalm
credo - Interactive guide to available topics and workflows
/role-clear
Role clear
credo - Clear this session's default role (back to no role; the agent does everything)
/role-plan
Role plan
credo - Set this session's default role to plan/clarify (owns clarifying 1_clarify items, no commits/push)
/role-task
Role task
credo - Set this session's default role to task/build (owns implementing GO items incl. commits/push per dogma)
/sandbox-promote
Sandbox promote
credo - Promote an accepted sandbox artifact from .credo/sandbox-tmp/ to .credo/sandbox/
/session-active
Session active
credo - Set the session mode to active (intensive live collaboration, no keep-alive)
/session-autonomous
Session autonomous
credo - Set the session mode to autonomous (work approved GO items unattended, hook-enforced keep-alive ON)
/session-init
Session init
credo - Initialize session with main agent workflow instructions
/session-passive
Session passive
credo - Set the session mode to passive (user available for clarifications only, no keep-alive)
/setup
Setup
credo - Set up Claude Code with recommended workflows and plugins
/cleanup
Cleanup
dogma - Find and fix AI-typical patterns in code (reactive cleanup)
/docs-update
Docs update
dogma - Sync documentation across README files and wiki articles
/force
Force
dogma - Interactively collect and apply CLAUDE rules to the project
/ignore
Ignore
dogma - Add ignore patterns to multiple locations at once
Make any song you can imagine
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