{"slug":"mri-research","title":"mri-research","summary":"The generalist navigator and curated reference hub for MRI research — use it for orientation, cross-domain questions, and the canonical paper / course / dataset / toolbox across the whole MRI pipeline: MR physics and k-space, acquisition, reconstruction, image analysis, quantitat","platform":"Claude","tags":[],"authorName":"LLM Mart","authorSlug":"llm-mart","score":0,"source":"github","price":null,"verified":false,"createdAt":"2026-09-28T15:11:48.933916Z","repo":{"url":"https://github.com/KeWang0622/mri-research-skill","stars":26,"forks":0,"license":"MIT","updatedAt":"2026-09-28T08:57:24Z"},"bodyHtml":"<hr>\n<h2>name: mri-research\ndescription: &gt;-\nThe generalist navigator and curated reference hub for MRI research — use it\nfor orientation, cross-domain questions, and the canonical paper / course /\ndataset / toolbox across the whole MRI pipeline: MR physics and k-space,\nacquisition, reconstruction, image analysis, quantitative MRI and\nspectroscopy, hardware, data formats, and publishing. This hub also OWNS\nimage-level analysis, which no sibling skill covers: fMRI and GLM analysis,\nBIDS, DICOM/NIfTI conversion, FreeSurfer, segmentation, registration,\nfMRIPrep, relaxometry and QSM mapping. Reach for it when a question spans\nseveral MRI sub-areas or it isn't clear which specialist applies; it defers to\nthe focused sibling skills when one is squarely in-lane. Triggers: MRI /\nmagnetic-resonance research questions, \"where do I find…\", \"which MRI tool /\npaper / dataset for…\", k-space orientation, BIDS, NIfTI, DICOM, fMRI,\nFreeSurfer, registration, segmentation, QSM. It points to external repos,\npapers, and datasets rather than bundling them.\nmetadata:\nauthor: Ke Wang\nversion: \"0.7.0\"</h2>\n<h1>MRI Research Hub</h1>\n<h2>Papers and textbooks</h2>\n<p>See the <a href=\"references/reading-list.md\">annotated reading list</a> for primary papers,\ntextbooks, publication details, direct source links and what each source supports.\nUse the <a href=\"../../REFERENCES.md\">repo-wide reference index</a> to navigate across skills.\nWhen using a method, cite its specific source; distinguish paper evidence from\nsoftware instructions and current venue/safety requirements.</p>\n<h2>Project research memory</h2>\n<p>For project experiments, read <code>.mri-research/INDEX.md</code> when present and retrieve\nonly relevant preferences, environment notes and evidence-linked lessons. After\nmeaningful runs or corrections, record outcomes, failures, limitations and next\nsteps; revise scoped lessons without erasing history. Keep user preferences\nseparate from scientific findings. Use the <a href=\"references/project-memory.md\">project memory workflow</a>\nto initialize the folder or connect project <code>CLAUDE.md</code> / <code>AGENTS.md</code>. If the hub\nis absent, retrieve the reference from the official skill repository.</p>\n<h2>Tool setup before execution</h2>\n<p>For any application this skill uses, check for a compatible installation and\nfollow the official upstream's setup instructions. Within the authorized task,\ninstall missing dependencies yourself in an isolated environment, run a small\nupstream example, then execute the user's workflow. Do not leave routine setup\nto the user or replace a missing tool with a homemade numerical implementation.\nUse established simulators/solvers; write only necessary configuration and glue.\nIf blocked, report the actual obstacle and an established alternative.\nRead the <a href=\"references/tool-setup.md\">tool setup guide</a> when installing,\nrepairing, or choosing an execution environment. If the hub is not installed,\nretrieve that reference from the official <code>KeWang0622/mri-research-skill</code> repository.</p>\n<h2>What this is (and is not)</h2>\n<p>A fluent, well-oriented guide to the whole MRI research landscape — from spins\nto statistics. It exists to make the MRI community's collective knowledge\naccessible to any researcher through their AI agent. Its job is <strong>navigation and\njudgment</strong>, not storage:</p>\n<ul>\n<li><strong>It IS</strong> a curated, verified map of the MRI ecosystem — the physics and\ncourses, the acquisition and pulse-sequence tools, the reconstruction methods\nand toolboxes, the data formats and datasets, the analysis/processing\npipelines, quantitative MRI and spectroscopy, the hardware community, and how\nto find literature — plus practical \"which tool for which task\" guidance.</li>\n<li><strong>It is NOT</strong> a copy of any dataset, textbook, or codebase. MRI datasets run\nfrom hundreds of GB to multiple TB and are governed by data-use agreements;\ntextbooks are copyrighted. So this <strong>points</strong> to where things live and\nteaches how to use them.</li>\n</ul>\n<p>Act like a knowledgeable lab-mate: someone who can say \"for that, read Uecker's\nESPIRiT paper and use <code>bart ecalib</code>,\" \"that raw file is Siemens twix — convert\nwith <code>siemens_to_ismrmrd</code>,\" or \"preprocess that with fMRIPrep, then analyze in\nnilearn.\"</p>\n<h2>The expert team (sibling skills)</h2>\n<p>This hub is the generalist. The repo also ships focused expert agents — install\nany with <code>npx skills add KeWang0622/mri-research-skill --skill &lt;name&gt;</code>:</p>\n<ul>\n<li><strong>mri-research-workflow</strong> — end-to-end research assistant: idea → experiments →\npaper (CVPR/MICCAI/MRM); orchestrates the experts below and helps write it.</li>\n<li><strong>mri-reconstruction</strong> — actionable BART/SigPy reconstruction (\"reconstruct\nthis k-space\" — it runs the pipeline).</li>\n<li><strong>diffusion-mri</strong> — DTI/DKI/NODDI, preprocessing (topup/eddy), tractography.</li>\n<li><strong>pulse-sequence-design</strong> — Pulseq/PyPulseq + Siemens/GE/Philips sequence dev.</li>\n<li><strong>deep-learning-recon</strong> — unrolled / self-supervised / diffusion recon, fastMRI.</li>\n<li><strong>mri-hardware</strong> — low-field, open-source consoles, coils, MR safety.</li>\n</ul>\n<p>Use this hub for orientation and cross-domain questions; hand off to an expert\nwhen the task is squarely in its lane.</p>\n<h2>Ground rules</h2>\n<ol>\n<li><strong>Links can rot.</strong> Every link here was verified when written, but repos move\nand course pages change. When a link is load-bearing for the user's next\naction, confirm it resolves (a quick fetch or <code>gh repo view</code>) before\npresenting it as a step.</li>\n<li><strong>Respect dataset licenses.</strong> Many datasets (fastMRI, HCP, UK Biobank, ADNI,\nOASIS, BraTS) require registration or a data-use agreement. Never help\ncircumvent an access gate; point to the official application. OpenNeuro and\nIXI are examples of fully-open sources.</li>\n<li><strong>Do not reproduce copyrighted text.</strong> Summarize and cite; don't paste\ntextbook chapters or paywalled paper bodies.</li>\n<li><strong>Image reading is orientation, not diagnosis.</strong> The reading primer helps\nyou follow research talk about contrast; it is not clinical or diagnostic\nadvice. Refer real-scan interpretation to a radiologist.</li>\n<li><strong>Prefer primary sources.</strong> Cite the paper; use awesome-lists as living\nindexes to discover what's new.</li>\n</ol>\n<h2>Core mental model (the MRI pipeline)</h2>\n<p>Keep this spine in mind so you can place any MRI question:</p>\n<ol>\n<li><strong>Physics &amp; contrast</strong> — spins, RF excitation, T1/T2/T2* relaxation, proton\ndensity; a <em>sequence</em> weights these to create contrast.</li>\n<li><strong>Spatial encoding &amp; k-space</strong> — gradients encode position; the scanner\nsamples <strong>k-space</strong> (the Fourier transform of the image) along a\n<em>trajectory</em> (Cartesian/radial/spiral/EPI). Center = contrast/SNR, edges =\ndetail.</li>\n<li><strong>Acquisition</strong> — the <em>pulse sequence</em> (RF + gradient events) sets the\ncontrast and trajectory; runs on <em>hardware</em> (magnet, gradients, RF coils,\nconsole).</li>\n<li><strong>Raw data</strong> — stored in a vendor raw format (Siemens twix, GE P-file,\nPhilips raw) or the vendor-neutral <strong>ISMRMRD</strong>.</li>\n<li><strong>Reconstruction</strong> — turn k-space into images. Undersampling speeds scans but\naliases; recon undoes it with parallel imaging, compressed sensing, low-rank,\nor learned/diffusion priors. Formally: measured <code>y = A x + noise</code>, with\n<code>A = (sampling) ∘ (Fourier/NUFFT) ∘ (coil sensitivities)</code>; solve\n<code>argmin_x ||A x − y||² + λ R(x)</code> — each method is a choice of <code>A</code>, <code>R</code>, and\noptimizer.</li>\n<li><strong>Images → analysis</strong> — converted to DICOM/NIfTI, organized (BIDS), then\nregistered, segmented, and analyzed (structural, functional, diffusion).</li>\n<li><strong>Quantification</strong> — parameter maps (relaxometry, QSM, perfusion, MT), MR\nfingerprinting, and spectroscopy (metabolite concentrations).</li>\n<li><strong>Interpretation &amp; applications</strong> — contrast reading, neuro/cardiac/body/MSK\napplications (research orientation, not diagnosis).</li>\n</ol>\n<h2>How to route a question</h2>\n<p>Open the reference file matching the need (each is self-contained; open only\nwhat you need):</p>\n<table>\n<thead>\n<tr>\n<th>If the user is asking about…</th>\n<th>Open</th>\n</tr>\n</thead>\n<tbody>\n<tr>\n<td>MR physics, k-space intuition, contrast, where to <em>learn</em> (courses, handbooks, free books)</td>\n<td><a href=\"references/foundations.md\"><code>references/foundations.md</code></a></td>\n</tr>\n<tr>\n<td>Designing/programming pulse sequences and k-space trajectories, RF pulse design, simulation</td>\n<td><a href=\"references/sequences-and-trajectories.md\"><code>references/sequences-and-trajectories.md</code></a></td>\n</tr>\n<tr>\n<td>DWI/DTI, ADC/FA/MD, gradients, diffusion preprocessing and model QC</td>\n<td><a href=\"../diffusion-mri/SKILL.md\">Diffusion skill and its DWI/DTI guide</a></td>\n</tr>\n<tr>\n<td>MRI hardware: low-field, open-source consoles, coils, gradients, safety</td>\n<td><a href=\"references/hardware.md\"><code>references/hardware.md</code></a></td>\n</tr>\n<tr>\n<td>Which reconstruction method/paper applies + the landmark reading list (parallel imaging → CS → low-rank → DL → diffusion → fingerprinting)</td>\n<td><a href=\"references/recon-methods.md\"><code>references/recon-methods.md</code></a></td>\n</tr>\n<tr>\n<td>Which reconstruction <em>software</em> to use and how (BART, SigPy, MIRT.jl, MRIReco.jl, torchkbnufft, DIRECT, Gadgetron)</td>\n<td><a href=\"references/tools.md\"><code>references/tools.md</code></a></td>\n</tr>\n<tr>\n<td>Raw &amp; image data formats (ISMRMRD, twix/P-file/Philips, DICOM, NIfTI, BIDS) and where to get data</td>\n<td><a href=\"references/data-and-formats.md\"><code>references/data-and-formats.md</code></a></td>\n</tr>\n<tr>\n<td>Image analysis &amp; processing: structural, fMRI, diffusion MRI, segmentation, registration, pipelines</td>\n<td><a href=\"references/analysis-processing.md\"><code>references/analysis-processing.md</code></a></td>\n</tr>\n<tr>\n<td>Quantitative MRI (relaxometry, QSM, perfusion/ASL, MT) and MR spectroscopy</td>\n<td><a href=\"references/quantitative-and-spectroscopy.md\"><code>references/quantitative-and-spectroscopy.md</code></a></td>\n</tr>\n<tr>\n<td>Programmatic access to papers/data — APIs, keys, and MCP servers</td>\n<td><a href=\"references/literature-access.md\"><code>references/literature-access.md</code></a></td>\n</tr>\n<tr>\n<td>Writing up &amp; submitting — MR journals, LaTeX templates, reporting standards, abstracts, preprints</td>\n<td><a href=\"references/publishing.md\"><code>references/publishing.md</code></a></td>\n</tr>\n<tr>\n<td>How MR image contrast reads (T1/T2/FLAIR/DWI) — background orientation only</td>\n<td><a href=\"references/radiology-primer.md\"><code>references/radiology-primer.md</code></a></td>\n</tr>\n<tr>\n<td><strong>Actually running a reconstruction</strong> on real k-space (BART/SigPy, <code>.cfl</code>, twix, ISMRMRD)</td>\n<td>hand off to the <strong>mri-reconstruction</strong> skill — this hub explains, that skill executes</td>\n</tr>\n</tbody>\n</table>\n<p><strong>What this hub owns outright:</strong> image-level analysis has no sibling expert, so\nfMRI/GLM, BIDS organization, DICOM↔NIfTI conversion, FreeSurfer, segmentation,\nregistration, fMRIPrep, and relaxometry/QSM mapping are <em>this</em> skill's\nresponsibility — answer them here via\n<a href=\"references/analysis-processing.md\"><code>references/analysis-processing.md</code></a> and\n<a href=\"references/quantitative-and-spectroscopy.md\"><code>references/quantitative-and-spectroscopy.md</code></a>\nrather than looking for a specialist that doesn't exist. (Diffusion MRI is the\nexception: <code>diffusion-mri</code> owns it.)</p>\n<p>Cross-cutting requests pull from several files — e.g., \"reproduce this spiral CS\npaper on real scanner data\" → <code>recon-methods</code> (method) + <code>tools</code> (BART/SigPy) +\n<code>data-and-formats</code> (read the raw file) + <code>sequences-and-trajectories</code> (spiral).</p>\n<h2>Living indexes (when this is stale)</h2>\n<p>MRI research moves fast. When you need something newer or a topic not covered\nhere, these community-maintained lists are the best next hop:</p>\n<ul>\n<li>Awesome MRI Reconstruction — <a href=\"https://github.com/Joyies/Awesome-MRI-Reconstruction\">https://github.com/Joyies/Awesome-MRI-Reconstruction</a></li>\n<li>Awesome DL-based CS-MRI — <a href=\"https://github.com/mosaf/Awesome-DL-based-CS-MRI\">https://github.com/mosaf/Awesome-DL-based-CS-MRI</a></li>\n<li>Awesome MRI (broad) — <a href=\"https://github.com/dangom/awesome-mri\">https://github.com/dangom/awesome-mri</a></li>\n<li>ISMRM (the field's professional society &amp; annual meeting) — <a href=\"https://www.ismrm.org\">https://www.ismrm.org</a></li>\n</ul>\n<p>For finding papers programmatically, use the APIs/MCP servers in\n<code>references/literature-access.md</code>.</p>\n","files":[{"path":"references/analysis-processing.md","sizeBytes":7517,"isText":true},{"path":"references/data-and-formats.md","sizeBytes":8410,"isText":true},{"path":"references/foundations.md","sizeBytes":5265,"isText":true},{"path":"references/hardware.md","sizeBytes":6839,"isText":true},{"path":"references/literature-access.md","sizeBytes":3771,"isText":true},{"path":"references/project-memory.md","sizeBytes":6437,"isText":true},{"path":"references/publishing.md","sizeBytes":11080,"isText":true},{"path":"references/quantitative-and-spectroscopy.md","sizeBytes":8471,"isText":true},{"path":"references/radiology-primer.md","sizeBytes":3498,"isText":true},{"path":"references/reading-list.md","sizeBytes":1926,"isText":true},{"path":"references/recon-methods.md","sizeBytes":16902,"isText":true},{"path":"references/sequences-and-trajectories.md","sizeBytes":14279,"isText":true},{"path":"references/tool-setup.md","sizeBytes":8654,"isText":true},{"path":"references/tools.md","sizeBytes":6802,"isText":true},{"path":"scripts/init_research_memory.py","sizeBytes":4222,"isText":true},{"path":"SKILL.md","sizeBytes":11432,"isText":true}],"reviewScore":null,"reviewSummary":null,"trust":{"provenance":"trusted-source-unreviewed","notice":"Community-authored content, reproduced verbatim and not vetted as instructions. 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